IL-17/IL-17A Antibody | R&D Systems AF-317 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

IL-17/IL-17A Antibody

catalog :

AF-317

quantity :

25 ug

price :

129 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation

citations: 14

Reference
Tiirikainen M, Woetmann A, Norsgaard H, Santamaria Babi L, Lovato P. Ex vivo culture of lesional psoriasis skin for pharmacological testing. J Dermatol Sci. 2020;97:109-116 pubmed publisher
Fania L, Morelli M, Scarponi C, Mercurio L, Scopelliti F, Cattani C, et al. Paradoxical psoriasis induced by TNF-α blockade shows immunological features typical of the early phase of psoriasis development. J Pathol Clin Res. 2020;6:55-68 pubmed publisher
Khalmuratova R, Shin H, Kim D, Park J. Interleukin (IL)-13 and IL-17A contribute to neo-osteogenesis in chronic rhinosinusitis by inducing RUNX2. EBioMedicine. 2019;46:330-341 pubmed publisher
Boxberg M, Leising L, Steiger K, Jesinghaus M, Alkhamas A, Mielke M, et al. Composition and Clinical Impact of the Immunologic Tumor Microenvironment in Oral Squamous Cell Carcinoma. J Immunol. 2018;: pubmed publisher
Rios D, Valva P, Casciato P, Frias S, Soledad Caldirola M, Gaillard M, et al. Chronic hepatitis C liver microenvironment: role of the Th17/Treg interplay related to fibrogenesis. Sci Rep. 2017;7:13283 pubmed publisher
Junginger J, Raue K, Wolf K, Janecek E, Stein V, Tipold A, et al. Zoonotic intestinal helminths interact with the canine immune system by modulating T cell responses and preventing dendritic cell maturation. Sci Rep. 2017;7:10310 pubmed publisher
Pellegrini C, Orlandi A, Costanza G, Di Stefani A, Piccioni A, Di Cesare A, et al. Expression of IL-23/Th17-related cytokines in basal cell carcinoma and in the response to medical treatments. PLoS ONE. 2017;12:e0183415 pubmed publisher
Seebauer C, Brunner S, Glockzin G, Piso P, Ruemmele P, Schlitt H, et al. Peritoneal carcinomatosis of colorectal cancer is characterized by structural and functional reorganization of the tumor microenvironment inducing senescence and proliferation arrest in cancer cells. Oncoimmunology. 2016;5:e1242543 pubmed publisher
Fattahi F, Brandsma C, Lodewijk M, Reinders Luinge M, Postma D, Timens W, et al. Atopy and Inhaled Corticosteroid Use Associate with Fewer IL-17+ Cells in Asthmatic Airways. PLoS ONE. 2016;11:e0161433 pubmed publisher
Mariuzzi L, Domenis R, Orsaria M, Marzinotto S, Londero A, Bulfoni M, et al. Functional expression of aryl hydrocarbon receptor on mast cells populating human endometriotic tissues. Lab Invest. 2016;96:959-971 pubmed publisher
Millar N, Akbar M, Campbell A, Reilly J, Kerr S, McLean M, et al. IL-17A mediates inflammatory and tissue remodelling events in early human tendinopathy. Sci Rep. 2016;6:27149 pubmed publisher
Nussbaumer Ochsner Y, Stolk J, Ferraz da Silva L, van Schadewijk A, de Jeu R, Prins F, et al. Association of Lung Inflammatory Cells with Small Airways Function and Exhaled Breath Markers in Smokers - Is There a Specific Role for Mast Cells?. PLoS ONE. 2015;10:e0129426 pubmed publisher
Punt S, Houwing Duistermaat J, Schulkens I, Thijssen V, Osse E, de Kroon C, et al. Correlations between immune response and vascularization qRT-PCR gene expression clusters in squamous cervical cancer. Mol Cancer. 2015;14:71 pubmed publisher
Martin M, Kesselring R, Saidou B, Brunner S, Schiechl G, Mouris V, et al. RORÎ³t(+) hematopoietic cells are necessary for tumor cell proliferation during colitis-associated tumorigenesis in mice. Eur J Immunol. 2015;45:1667-79 pubmed publisher

product information

brand :

R&D Systems

SKU :

AF-317

product name :

IL-17/IL-17A Antibody

unit sizes :

25 ug

description :

The Human IL-17/IL-17A Antibody from R&D Systems is a goat polyclonal antibody to IL-17/IL-17A. This antibody reacts with human. The Human IL-17/IL-17A Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunoprecipitation, Neutralization, Intracellular Staining by Flow Cytometry, Immunocytochemistry, CyTOF-ready.

target :

IL-17/IL-17A

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant human IL-17, Ile20-Ala155, Accession # Q16552

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human

specificity :

Detects human IL-17 in direct ELISAs and Western blots. In direct ELISAs, approximately 30% cross-reactivity with recombinant canine IL-17 is observed, approximately 10% cross-reactivity with recombinant human IL-17F is observed and less than 5% cross-reactivity with recombinant mouse IL-17 is observed.

gene symbol :

IL17A

details of functionality :

ActivityAssaywCitation not found None None None None None None

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

AF-317-NA

accessionNumbers :

Q16552

applications :

Western Blot, Immunohistochemistry, Immunoprecipitation, Neutralization, Intracellular Staining by Flow Cytometry, Immunocytochemistry, CyTOF-ready

USD :

129 USD

applications abr :

WB, IHC, IP, Neut, ICFlow, ICC, CyTOF-ready

alt names :

CTLA8, CTLA-8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL17A, IL-17A, IL-17Acytotoxic T-lymphocyte-associated protein 8, IL-17CTLA-8, IL17interleukin-17A, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.