Human IL-17/IL-17A Antibody | R&D Systems AF-317-NA product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-17/IL-17A Antibody

catalog :

AF-317-NA

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, dogs

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 33

Reference
Rosenzweig N, Kleemann K, Rust T, Carpenter M, Grucci M, Aronchik M, et al. Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease. Nat Med. 2024;30:2990-3003 pubmed publisher
Tsukalov I, S xe1 nchez Cerrillo I, Rajas O, Ávalos E, Iturricastillo G, Esparcia L, et al. NFκB and NLRP3/NLRC4 inflammasomes regulate differentiation, activation and functional properties of monocytes in response to distinct SARS-CoV-2 proteins. Nat Commun. 2024;15:2100 pubmed publisher
van Eijs M, Ter Linde J, Baars M, Amini M, Lacl xe9 M, Brand E, et al. Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor colitis. iScience. 2023;26:107891 pubmed publisher
Carbone M, Capone A, Guercio M, Reddel S, Silvestris D, Lulli D, et al. Insight into immune profile associated with vitiligo onset and anti-tumoral response in melanoma patients receiving anti-PD-1 immunotherapy. Front Immunol. 2023;14:1197630 pubmed publisher
Oyler B, Valencia D xe1 vila J, Moysi E, Molyvdas A, Ioannidou K, March K, et al. Multilevel human secondary lymphoid immune system compartmentalization revealed by complementary imaging approaches. iScience. 2023;26:107261 pubmed publisher
Liu X, Xu C, Guo T, Zhan S, Quan Q, Li M, et al. Clinical significance of CD155 expression and correlation with cellular components of tumor microenvironment in gastric adenocarcinoma. Front Immunol. 2023;14:1173524 pubmed publisher
Chen J, Murphy M, Singh K, Wang A, Chow R, Kim S, et al. IL17A mRNA Staining Distinguishes Palmoplantar Psoriasis from Hyperkeratotic Palmoplantar Eczema in Diagnostic Skin Biopsies. JID Innov. 2023;3:100189 pubmed publisher
Bossart S, Seyed Jafari S, Heidemeyer K, Yan K, Feldmeyer L, Borradori L, et al. Canakinumab leads to rapid reduction of neutrophilic inflammation and long-lasting response in Schnitzler syndrome. Front Med (Lausanne). 2023;10:1050230 pubmed publisher
Sch xe4 bitz A, Hillig C, Mubarak M, Jargosch M, Farnoud A, Scala E, et al. Spatial transcriptomics landscape of lesions from non-communicable inflammatory skin diseases. Nat Commun. 2022;13:7729 pubmed publisher
Zheng N, Fang J, Xue G, Wang Z, Li X, Zhou M, et al. Induction of tumor cell autosis by myxoma virus-infected CAR-T and TCR-T cells to overcome primary and acquired resistance. Cancer Cell. 2022;40:973-985.e7 pubmed publisher
Verhoeven B, Mei S, Olsen T, Gustafsson K, Valind A, Lindstr xf6 m A, et al. The immune cell atlas of human neuroblastoma. Cell Rep Med. 2022;3:100657 pubmed publisher
Theocharidis G, Thomas B, Sarkar D, Mumme H, Pilcher W, Dwivedi B, et al. Single cell transcriptomic landscape of diabetic foot ulcers. Nat Commun. 2022;13:181 pubmed publisher
Krijgsman D, Sinha N, Baars M, van Dam S, Amini M, Vercoulen Y. MATISSE: An analysis protocol for combining imaging mass cytometry with fluorescence microscopy to generate single-cell data. STAR Protoc. 2022;3:101034 pubmed publisher
Tosi A, Nardinocchi L, Carbone M, Capriotti L, Pagani E, Mastroeni S, et al. Reduced Interleukin-17-Expressing Cells in Cutaneous Melanoma. Biomedicines. 2021;9: pubmed publisher
Kelley C, Pollack I, Yacoub R, Zhu Z, Van Doren V, Gumber S, et al. Condomless receptive anal intercourse is associated with markers of mucosal inflammation in a cohort of men who have sex with men in Atlanta, Georgia. J Int AIDS Soc. 2021;24:e25859 pubmed publisher
Li J, Cheng L, Jia H, Liu C, Wang S, Liu Y, et al. IFN-γ facilitates liver fibrogenesis by CD161+CD4+ T cells through a regenerative IL-23/IL-17 axis in chronic hepatitis B virus infection. Clin Transl Immunology. 2021;10:e1353 pubmed publisher
Rios D, Casciato P, Caldirola M, Gaillard M, Giadans C, Ameigeiras B, et al. Chronic Hepatitis C Pathogenesis: Immune Response in the Liver Microenvironment and Peripheral Compartment. Front Cell Infect Microbiol. 2021;11:712105 pubmed publisher
Lamb D, De Sousa D, Quast K, Fundel Clemens K, Erjefalt J, Sandén C, et al. RORγt inhibitors block both IL-17 and IL-22 conferring a potential advantage over anti-IL-17 alone to treat severe asthma. Respir Res. 2021;22:158 pubmed publisher
Cairoli V, De Matteo E, Rios D, Lezama C, Galoppo M, Casciato P, et al. Hepatic lymphocytes involved in the pathogenesis of pediatric and adult non-alcoholic fatty liver disease. Sci Rep. 2021;11:5129 pubmed publisher
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product information

brand :

R&D Systems

master code :

AF-317-NA

SKU :

AF-317-NA

product name :

Human IL-17/IL-17A Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human IL-17/IL-17A Antibody from R&D Systems is a goat polyclonal antibody to IL-17/IL-17A. This antibody reacts with canine,human,mouse. The Human IL-17/IL-17A Antibody has been validated for the following applications: Immunohistochemistry,Immunocytochemistry,ELISA Development,Tissue Culture,Flow Cytometry,Western Blot,Neutralization,Cell Culture,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunoprecipitation,Intracellular Staining by Flow Cytometry,CyTOF-ready.

target :

IL-17/IL-17A

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Immunohistochemistry 1-15 ug/mL, Immunoprecipitation 3 ug/100 ug cell lysate, Neutralization 0.02-0.12 ug/mL, Intracellular Staining by Flow Cytometry 2.5 ug/10^6 cells, Immunocytochemistry 5-15 ug/mL, CyTOF-ready

host :

Goat

immunogen :

E. coli -derived recombinant human IL-17, Ile20-Ala155, Accession # Q16552

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Canine,Human,Mouse

specificity :

Detects human IL-17 in direct ELISAs and Western blots. In direct ELISAs, approximately 30% cross-reactivity with recombinant canine IL-17 is observed.

gene symbol :

IL17A

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Human IL-17 antibody by Western Blot.

accessionNumbers :

Q16552

applications :

Immunoprecipitation,Intracellular Staining by Flow Cytometry,CyTOF-ready,ELISA Development,Tissue Culture,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry,Cell Culture

USD :

509 USD

alt names :

CTLA8, CTLA-8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL17A, IL-17A, IL-17Acytotoxic T-lymphocyte-associated protein 8, IL-17CTLA-8, IL17interleukin-17A, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage