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company name :
R&D Systems
product type :
antibody
product name :
Human HGF Antibody
catalog :
AF-294-NA
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 12
Reference
Erlmeier M, Mikuteit M, Zsch xe4 bitz S, Autenrieth M, Weichert W, Hartmann A, et al. Immunohistochemical expression of the hepatocyte growth factor in chromophobe renal cell carcinoma. BMC Urol. 2023;23:90 pubmed publisher
Igarashi N, Miyata K, Loo T, Chiba M, Hanyu A, Nishio M, et al. Hepatocyte growth factor derived from senescent cells attenuates cell competition-induced apical elimination of oncogenic cells. Nat Commun. 2022;13:4157 pubmed publisher
Sharma S, Watanabe T, Nishimoto T, Takihara T, Mlakar L, Nguyen X, et al. E4 engages uPAR and enolase-1 and activates urokinase to exert antifibrotic effects. JCI Insight. 2021;6: pubmed publisher
Yamaguchi Y, Ohshima M. Local administration of anti-hepatocyte growth factor-neutralizing antibody reverts naturally occurring periodontitis. J Oral Biosci. 2021;63:245-252 pubmed publisher
Cheng N, Tu Y, Lee N, Young T. Influence of Human Platelet Lysate on Extracellular Matrix Deposition and Cellular Characteristics in Adipose-Derived Stem Cell Sheets. Front Cell Dev Biol. 2020;8:558354 pubmed publisher
Yang T, Zhiheng H, Zhanhuai W, Qian X, Yue L, Xiaoxu G, et al. Increased RAB31 Expression in Cancer-Associated Fibroblasts Promotes Colon Cancer Progression Through HGF-MET Signaling. Front Oncol. 2020;10:1747 pubmed publisher
Lee E, Hwang I, Lee J, Park J, Kim K, Kim I, et al. Hepatic stellate cell-specific knockout of transcriptional intermediary factor 1γ aggravates liver fibrosis. J Exp Med. 2020;217: pubmed publisher
Qiu S, Van Rooijen J, Nienhuis H, van der Vegt B, Timmer Bosscha H, van Leeuwen Stok E, et al. High hepatocyte growth factor expression in primary tumor predicts better overall survival in male breast cancer. Breast Cancer Res. 2020;22:30 pubmed publisher
Tamberg T, Hong Z, De Schepper D, Skovbjerg S, Dupont D, Vitved L, et al. Blocking the proteolytic activity of zymogen matriptase with antibody-based inhibitors. J Biol Chem. 2019;294:314-326 pubmed publisher
Chang H, Kim P, Kim D, Cho H, Jeong M, Kim D, et al. Coronary stents with inducible VEGF/HGF-secreting UCB-MSCs reduced restenosis and increased re-endothelialization in a swine model. Exp Mol Med. 2018;50:114 pubmed publisher
Nagashima K, Miwa T, Soumiya H, Ushiro D, Takeda Kawaguchi T, Tamaoki N, et al. Priming with FGF2 stimulates human dental pulp cells to promote axonal regeneration and locomotor function recovery after spinal cord injury. Sci Rep. 2017;7:13500 pubmed publisher
Zoratti G, Tanabe L, Hyland T, Duhaime M, Colombo E, Leduc R, et al. Matriptase regulates c-Met mediated proliferation and invasion in inflammatory breast cancer. Oncotarget. 2016;7:58162-58173 pubmed publisher
product information
brand :
R&D Systems
master code :
AF-294-NA
SKU :
AF-294-NA
product name :
Human HGF Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human HGF Antibody from R&D Systems is a goat polyclonal antibody to HGF. This antibody reacts with canine,human,mouse,rat. The Human HGF Antibody has been validated for the following applications: Immunoassay Development,Immunocytochemistry,Immunoprecipitation,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin.
target :
HGF
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.1 ug/mL, Immunohistochemistry 5-15 ug/mL, Neutralization 0.01-.06 ug/mL
host :
Goat
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human HGF, Gln32-Ser728 (Asp384Asn, Asp416Asn, Leu622Ser, His645Arg, Val678Ile), Accession # P14210
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Canine,Human,Mouse,Rat
specificity :
Detects human HGF in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant mouse HGF is observed. In Western blots, no cross-reactivity with recombinant canine HGF is observed.
gene symbol :
HGF
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Recombinant Human HGF antibody by Western Blot.
accessionNumbers :
P14210
applications :
Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Neutralization,Immunocytochemistry
USD :
489 USD
alt names :
deafness, autosomal recessive 39, DFNB39, EC 3.4.21, EC 3.4.21.7, fibroblast-derived tumor cytotoxic factor, F-TCF, hepatocyte growth factor (hepapoietin A; scatter factor), Hepatopoeitin-A, Hepatopoietin A, HGFB, HPTA, HPTAhepatocyte growth factor, lung fibroblast-derived mitogen, Scatter factor, SF, SFhepatopoeitin-A
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.