This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
VEGF 165 Antibody
catalog :
AF-293
quantity :
25 ug
price :
129 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization
citations: 10
Reference
Njau F, Shushakova N, Schenk H, Wulfmeyer V, Bollin R, Menne J, et al. Calcium dobesilate reduces VEGF signaling by interfering with heparan sulfate binding site and protects from vascular complications in diabetic mice. PLoS ONE. 2020;15:e0218494 pubmed publisher
Pehrsson S, Hölttä M, Linhardt G, Danielson R, Carlsson L. Rapid Production of Human VEGF-A following Intradermal Injection of Modified VEGF-A mRNA Demonstrated by Cutaneous Microdialysis in the Rabbit and Pig In Vivo. Biomed Res Int. 2019;2019:3915851 pubmed publisher
Donzelli S, Milano E, Pruszko M, Sacconi A, Masciarelli S, Iosue I, et al. Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages. Breast Cancer Res. 2018;20:59 pubmed publisher
Jalili R, Horecka J, Swartz J, Davis R, Persson H. Streamlined circular proximity ligation assay provides high stringency and compatibility with low-affinity antibodies. Proc Natl Acad Sci U S A. 2018;115:E925-E933 pubmed publisher
Ikari J, Nelson A, Obaid J, Girón Martínez A, Ikari K, Makino F, et al. Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease. PLoS ONE. 2017;12:e0184039 pubmed publisher
Hettema W, Wynne C, Lang B, Altendorfer M, Czeloth N, Lohmann R, et al. A randomized, single-blind, Phase I trial (INVICTAN-1) assessing the bioequivalence and safety of BI 695502, a bevacizumab biosimilar candidate, in healthy subjects. Expert Opin Investig Drugs. 2017;26:889-896 pubmed publisher
Yang S, Qi F, Tang C, Wang H, Qin H, Li X, et al. CD147 promotes the proliferation, invasiveness, migration and angiogenesis of human lung carcinoma cells. Oncol Lett. 2017;13:898-904 pubmed publisher
Xu W, Li B, Guan X, Chung S, Wang Y, Yip Y, et al. Cancer cell-secreted IGF2 instigates fibroblasts and bone marrow-derived vascular progenitor cells to promote cancer progression. Nat Commun. 2017;8:14399 pubmed publisher
Zheng L, Zhao C, Du Y, Lin X, Jiang Y, Lee C, et al. PDGF-CC underlies resistance to VEGF-A inhibition and combinatorial targeting of both suppresses pathological angiogenesis more efficiently. Oncotarget. 2016;7:77902-77915 pubmed publisher
Gao Y, Zhou Z, Lu S, Huang X, Zhang C, Jiang R, et al. Chemokine CCL15 Mediates Migration of Human Bone Marrow-Derived Mesenchymal Stem Cells Toward Hepatocellular Carcinoma. Stem Cells. 2016;34:1112-22 pubmed publisher
product information
brand :
R&D Systems
SKU :
AF-293
product name :
VEGF 165 Antibody
unit sizes :
25 ug
description :
The Human VEGF165 Antibody from R&D Systems is a goat polyclonal antibody to VEGF. This antibody reacts with human. The Human VEGF165 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Neutralization, Immunocytochemistry.
target :
VEGF
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human VEGF165, Ala27-Arg191, Accession # NP_001165097.1
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human VEGF in direct ELISAs and Western blots. In direct ELISAs, approximately 100% cross-reactivity with recombinant canine VEGF is observed, and less than 20% cross-reactivity with recombinant mouse VEGF165 and recombinant rat VEGF164 is observed, and less than 5% cross-reactivity with recombinant zebrafish VEGF is observed.
gene symbol :
VEGFA
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
catalog number base :
AF-293-NA
accessionNumbers :
NP_001165097.1
applications :
Western Blot, Immunohistochemistry, Neutralization, Immunocytochemistry
USD :
129 USD
applications abr :
WB, IHC, Neut, ICC
alt names :
MVCD1, VAS, vascular endothelial growth factor A, Vascular permeability factor, Vasculotropin, VEGFA, VEGF-A, VEGFMGC70609, VPF, VPFvascular endothelial growth factor
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.