Human IGF-I/IGF-1 Antibody | R&D Systems AF-291-NA product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IGF-I/IGF-1 Antibody

catalog :

AF-291-NA

quantity :

250 ug (also 25 ug)

price :

539 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 18

Reference
Guan H, Yonemitsu I, Ikeda Y, Ono T. Reversible Effects of Functional Mandibular Lateral Shift on Masticatory Muscles in Growing Rats. Biomedicines. 2023;11: pubmed publisher
Tu X, Jain A, Parra Bueno P, Decker H, Liu X, Yasuda R. Local autocrine plasticity signaling in single dendritic spines by insulin-like growth factors. Sci Adv. 2023;9:eadg0666 pubmed publisher
Fonteneau G, Redding A, Hoag Lee H, Sim E, Heinrich S, Gaida M, et al. Stress Granules determine the Development of Obesity-associated Pancreatic Cancer. Cancer Discov. 2022;: pubmed publisher
Lugo Cintr xf3 n K, Ayuso J, Humayun M, Gong M, Kerr S, Ponik S, et al. Primary head and neck tumour-derived fibroblasts promote lymphangiogenesis in a lymphatic organotypic co-culture model. EBioMedicine. 2021;73:103634 pubmed publisher
Uruski P, Miku x142 a Pietrasik J, Paku x142 a M, Budkiewicz S, Drzewiecki M, Gaiday A, et al. Malignant Ascites Promote Adhesion of Ovarian Cancer Cells to Peritoneal Mesothelium and Fibroblasts. Int J Mol Sci. 2021;22: pubmed publisher
Zhang Q, Li T, Wang Z, Kuang X, Shao N, Lin Y. lncRNA NR2F1-AS1 promotes breast cancer angiogenesis through activating IGF-1/IGF-1R/ERK pathway. J Cell Mol Med. 2020;24:8236-8247 pubmed publisher
Alvarez Rivera F, Rey Rico A, Venkatesan J, Diaz Gomez L, Cucchiarini M, Concheiro A, et al. Controlled Release of rAAV Vectors from APMA-Functionalized Contact Lenses for Corneal Gene Therapy. Pharmaceutics. 2020;12: pubmed publisher
Haywood N, Slater T, Drozd M, Warmke N, Matthews C, Cordell P, et al. IGFBP-1 in Cardiometabolic Pathophysiology-Insights From Loss-of-Function and Gain-of-Function Studies in Male Mice. J Endocr Soc. 2020;4:bvz006 pubmed publisher
Lie S, Vieira B, Arruda S, Simões M, Ashander L, Furtado J, et al. Molecular Basis of The Retinal Pigment Epithelial Changes That Characterize The Ocular Lesion in Toxoplasmosis. Microorganisms. 2019;7: pubmed publisher
Morscheid S, Rey Rico A, Schmitt G, Madry H, Cucchiarini M, Venkatesan J. Therapeutic Effects of rAAV-Mediated Concomittant Gene Transfer and Overexpression of TGF-β and IGF-I on the Chondrogenesis of Human Bone-Marrow-Derived Mesenchymal Stem Cells. Int J Mol Sci. 2019;20: pubmed publisher
Pakuła M, Uruski P, Niklas A, Wozniak A, Szpurek D, Tykarski A, et al. A Unique Pattern of Mesothelial-Mesenchymal Transition Induced in the Normal Peritoneal Mesothelium by High-Grade Serous Ovarian Cancer. Cancers (Basel). 2019;11: pubmed publisher
Pristerá A, Blomeley C, Lopes E, Threlfell S, Merlini E, Burdakov D, et al. Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration. Proc Natl Acad Sci U S A. 2019;116:3817-3826 pubmed publisher
Pakuła M, Mikuła Pietrasik J, Witucka A, Kostka Jeziorny K, Uruski P, Moszyński R, et al. The Epithelial-Mesenchymal Transition Initiated by Malignant Ascites Underlies the Transmesothelial Invasion of Ovarian Cancer Cells. Int J Mol Sci. 2019;20: pubmed publisher
Dou L, Zheng Y, Li L, Gui X, Chen Y, Yu M, et al. The effect of cinnamon on polycystic ovary syndrome in a mouse model. Reprod Biol Endocrinol. 2018;16:99 pubmed publisher
Nagel S, Pommerenke C, Meyer C, Kaufmann M, MacLeod R, Drexler H. Aberrant expression of NKL homeobox gene HLX in Hodgkin lymphoma. Oncotarget. 2018;9:14338-14353 pubmed publisher
Wang D, Liu C, Wang J, Jia Y, Hu X, Jiang H, et al. Protein C receptor stimulates multiple signaling pathways in breast cancer cells. J Biol Chem. 2018;293:1413-1424 pubmed publisher
Song L, Sun Z, Kim D, Gou W, Strange C, Dong H, et al. Adipose stem cells from chronic pancreatitis patients improve mouse and human islet survival and function. Stem Cell Res Ther. 2017;8:192 pubmed publisher
Frisch J, Orth P, Rey Rico A, Venkatesan J, Schmitt G, Madry H, et al. Peripheral blood aspirates overexpressing IGF-I via rAAV gene transfer undergo enhanced chondrogenic differentiation processes. J Cell Mol Med. 2017;21:2748-2758 pubmed publisher

product information

brand :

R&D Systems

master code :

AF-291-NA

SKU :

AF-291-NA

product name :

Human IGF-I/IGF-1 Antibody

unit size :

250 ug (also 25 ug)

seo description :

The Human IGF-I/IGF-1 Antibody from R&D Systems is a goat polyclonal antibody to IGF-I/IGF-1. This antibody reacts with bovine,human,mouse,rat. The Human IGF-I/IGF-1 Antibody has been validated for the following applications: ELISA Development,ELISA Development (Detection),Immunoprecipitation,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Simple Western.

target :

IGF-I/IGF-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Simple Western 50 ug/mL, Immunohistochemistry 5-15 ug/mL, Neutralization 3-12 ug/mL, Immunocytochemistry 5-15 ug/mL

host :

Goat

immunogen :

E. coli -derived recombinant human IGF-I/IGF-1

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Bovine,Human,Mouse,Rat

specificity :

Detects human IGF-I/IGF-1 in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse IGF-I/IGF-1 and recombinant rat IGF-I/IGF-1 is observed.

gene symbol :

IGF1

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced by IGF-I/IGF-1 and Neutralization by Human IGF-I/IGF-1 Antibody.

applications :

Simple Western,ELISA Development,ELISA Development (Detection),Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry

USD :

539 USD

alt names :

IBP1, IGF1, IGF-1, IGF1A, IGFI, IGF-I, IGF-IA, IGF-IB, insulin-like growth factor 1, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor I, insulin-like growth factor IA, insulin-like growth factor IB, Mechano growth factor, MGF, Somatomedin A, Somatomedin C, Somatomedin-C

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage