product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human CCL2/JE/MCP-1 Antibody
catalog :
AF-279-NA
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, rat, rhesus macaque
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 6
Reference
Sinclair J, Vedelago C, Ryan F, Carney M, Redd M, Lynn M, et al. Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte function. Nat Microbiol. 2024;9:3135-3147 pubmed publisher
Lee T, Chen T, Kuo Y, Lan H, Yang M, Chu P. Tumor-associated tissue eosinophilia promotes angiogenesis and metastasis in head and neck squamous cell carcinoma. Neoplasia. 2023;35:100855 pubmed publisher
Wang L, Lan J, Tang J, Luo N. MCP-1 targeting: Shutting off an engine for tumor development. Oncol Lett. 2022;23:26 pubmed publisher
Peng W, Rao D, Zhang M, Shi Y, Wu J, Nie G, et al. Teneligliptin prevents doxorubicin-induced inflammation and apoptosis in H9c2 cells. Arch Biochem Biophys. 2020;683:108238 pubmed publisher
Collin de l Hortet A, Takeishi K, Guzman Lepe J, Morita K, Achreja A, Popovic B, et al. Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism. Cell Metab. 2019;30:385-401.e9 pubmed publisher
Bozzelli P, Yin T, Avdoshina V, Mocchetti I, CONANT K, Maguire Zeiss K. HIV-1 Tat promotes astrocytic release of CCL2 through MMP/PAR-1 signaling. Glia. 2019;67:1719-1729 pubmed publisher
product information
brand :
R&D Systems
master code :
AF-279-NA
SKU :
AF-279-NA
product name :
Human CCL2/JE/MCP-1 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human CCL2/JE/MCP-1 Antibody from R&D Systems is a goat polyclonal antibody to CCL2/JE/MCP-1. This antibody reacts with human,primate - macaca mulatta (rhesus macaque),rabbit,rat. The Human CCL2/JE/MCP-1 Antibody has been validated for the following applications: Bioassay,Western Blot,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Immunohistochemistry.
target :
CCL2/JE/MCP-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.1 ug/mL, Immunohistochemistry 10-25 ug/mL, Neutralization 1.5-4.5 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant human CCL2/JE/MCP-1, Gln24-Thr99, Accession # P13500
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Primate - Macaca mulatta (Rhesus Macaque),Rabbit,Rat
specificity :
Detects human CCL2/JE/MCP-1 in direct ELISAs and Western blots.
gene symbol :
CCL2
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Recombinant Human CCL2/JE/MCP-1 antibody by Western Blot.
accessionNumbers :
P13500
applications :
Immunohistochemistry,Bioassay,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry
USD :
499 USD
alt names :
C-C motif chemokine ligand 2, CCL2, GDCF-2, HC11, HSMCR30, MCAF, Mcp1, MCP-1, SCYA2, SMC-CF
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.