Human CCL5/RANTES Antibody | R&D Systems AF-278-NA product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CCL5/RANTES Antibody

catalog :

AF-278-NA

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rhesus macaque

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 11

Reference
Claireaux M, Robinot R, Kervevan J, Patgaonkar M, Staropoli I, Brelot A, et al. Low CCR5 expression protects HIV-specific CD4+ T cells of elite controllers from viral entry. Nat Commun. 2022;13:521 pubmed publisher
Sullivan G, Galdi P, Borbye Lorenzen N, Stoye D, Lamb G, Evans M, et al. Preterm Birth Is Associated With Immune Dysregulation Which Persists in Infants Exposed to Histologic Chorioamnionitis. Front Immunol. 2021;12:722489 pubmed publisher
Mladinich M, Conde J, Schutt W, Sohn S, Mackow E. Blockade of Autocrine CCL5 Responses Inhibits Zika Virus Persistence and Spread in Human Brain Microvascular Endothelial Cells. MBio. 2021;12:e0196221 pubmed publisher
Moreno H, Kunz S. The Protein Kinase Receptor Modulates the Innate Immune Response against Tacaribe Virus. Viruses. 2021;13: pubmed publisher
Sun Y, Wu L, Liu S, Jiang M, Hu B, Zhou K, et al. Dissecting spatial heterogeneity and the immune-evasion mechanism of CTCs by single-cell RNA-seq in hepatocellular carcinoma. Nat Commun. 2021;12:4091 pubmed publisher
Li X, Fang T, Xu S, Jin P, Zhou D, Wang Z, et al. PARP inhibitors promote stromal fibroblast activation by enhancing CCL5 autocrine signaling in ovarian cancer. NPJ Precis Oncol. 2021;5:49 pubmed publisher
Yoshida T, Miura T, Matsumiya T, Yoshida H, Morohashi H, Sakamoto Y, et al. Toll-Like Receptor 3 as a Recurrence Risk Factor and a Potential Molecular Therapeutic Target in Colorectal Cancer. Clin Exp Gastroenterol. 2020;13:427-438 pubmed publisher
Rodrigues Neves C, Spiekstra S, de Graaf N, Rustemeyer T, Feilzer A, Kleverlaan C, et al. Titanium salts tested in reconstructed human skin with integrated MUTZ-3-derived Langerhans cells show an irritant rather than a sensitizing potential. Contact Dermatitis. 2020;83:337-346 pubmed publisher
Frapin L, Clouet J, Ch xe9 deville C, Moraru C, Samarut E, Henry N, et al. Controlled release of biological factors for endogenous progenitor cell migration and intervertebral disc extracellular matrix remodelling. Biomaterials. 2020;253:120107 pubmed publisher
Singh S, Mishra M, Eltoum I, Bae S, Lillard J, Singh R. CCR5/CCL5 axis interaction promotes migratory and invasiveness of pancreatic cancer cells. Sci Rep. 2018;8:1323 pubmed publisher
Rump L, Mattey D, Kehoe O, Middleton J. An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium. Cytokine. 2017;97:133-140 pubmed publisher

product information

brand :

R&D Systems

master code :

AF-278-NA

SKU :

AF-278-NA

product name :

Human CCL5/RANTES Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human CCL5/RANTES Antibody from R&D Systems is a goat polyclonal antibody to CCL5/RANTES. This antibody reacts with human,mouse,primate - macaca mulatta (rhesus macaque). The Human CCL5/RANTES Antibody has been validated for the following applications: Flow Cytometry,Immunoprecipitation,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Simple Western.

target :

CCL5/RANTES

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Simple Western 10 ug/mL, Immunohistochemistry 5-15 ug/mL, Neutralization 0.1-0.4 ug/mL, Immunocytochemistry 5-15 ug/mL

host :

Goat

immunogen :

E. coli -derived recombinant human CCL5/RANTES, Ser24-Ser91, Accession # P13501

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Primate - Macaca mulatta (Rhesus Macaque)

specificity :

Detects human CCL5/RANTES in direct ELISAs. Detects human CCL5/RANTES and mouse CCL5/RANTES Western blots. In direct ELISAs, approximately 40% cross-reactivity with recombinant canine CCL5/RANTES is observed and approximately 20% cross-reactivity with recombinant cotton rat CCL5/RANTES is observed. In Western blots, no cross-reactivity with recombinant human (rh) CCL3 and rhCCL4 is observed.

gene symbol :

CCL5

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Recombinant Human and Mouse CCL5/RANTES antibody by Western Blot.

accessionNumbers :

P13501

applications :

Simple Western,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry

USD :

509 USD

alt names :

chemokine (C-C motif) ligand 5, D17S136Enormally T-expressed, and presumably secreted, EoCP, Eosinophil chemotactic cytokine, RANTES, SISd, SIS-delta, small inducible cytokine A5 (RANTES), small inducible cytokine subfamily A (Cys-Cys), member 5, Small-inducible cytokine A5, T cell-specific protein P228, T-cell specific protein p288, TCP228T-cell-specific protein RANTES

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage