product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human CCL3/MIP-1 alpha Antibody
catalog :
AF-270-NA
quantity :
100 ug (also 25 ug)
price :
539 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, neutralization, flow cytometry
more info or order :
R&D Systems product webpage
citations: 5
Reference
Kuczkowska K, Bjerkan L, Stubsrud E, Husbyn H, Chellappa S, Hauge A, et al. A novel SARS-CoV-2 Beta RBD DNA vaccine directly targeted to antigen-presenting cells induces strong humoral and T cell responses. Sci Rep. 2023;13:18902 pubmed publisher
Claireaux M, Robinot R, Kervevan J, Patgaonkar M, Staropoli I, Brelot A, et al. Low CCR5 expression protects HIV-specific CD4+ T cells of elite controllers from viral entry. Nat Commun. 2022;13:521 pubmed publisher
Toledo N, Li H, Omange R, Dacoba T, Crecente Campo J, Schalk D, et al. Cervico-Vaginal Inflammatory Cytokine and Chemokine Responses to Two Different SIV Immunogens. Front Immunol. 2020;11:1935 pubmed publisher
Kodama T, Koma Y, Arai N, Kido A, Urakawa N, Nishio M, et al. CCL3-CCR5 axis contributes to progression of esophageal squamous cell carcinoma by promoting cell migration and invasion via Akt and ERK pathways. Lab Invest. 2020;100:1140-1157 pubmed publisher
Leng T, Akther H, Hackstein C, Powell K, King T, Friedrich M, et al. TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions. Cell Rep. 2019;28:3077-3091.e5 pubmed publisher
product information
brand :
R&D Systems
master code :
AF-270-NA
SKU :
AF-270-NA
product name :
Human CCL3/MIP-1 alpha Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human CCL3/MIP-1 alpha Antibody from R&D Systems is a goat polyclonal antibody to CCL3/MIP-1 alpha. This antibody reacts with human. The Human CCL3/MIP-1 alpha Antibody has been validated for the following applications: Antibody Array Development,ELISA Development,Luminex Development,Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry,ELISA Capture (Matched Antibody Pair).
target :
CCL3/MIP-1 alpha
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.1 ug/mL, Immunohistochemistry 5-15 ug/mL, Neutralization 2-8 ug/mL, ELISA Capture (Matched Antibody Pair) 0.2-0.8 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant human CCL3/MIP-1 alpha , Ala27-Ala92, Accession # P10147
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human CCL3/MIP-1 alpha in ELISAs and Western blots. In sandwich immunoassays, less than 0.05% cross-reactivity with recombinant human (rh) MIP-1▀, rhMIP-1 delta , rhMIP-3 alpha , rhMIP-3▀, and recombinant mouse (rm) MIP-1 alpha is observed. Neutralizes the biological activity of recombinant human CCL3/MIP-1 alpha . In the chemotaxis assay this antibody will also partially neutralize the biological activity of rhMIP-1▀ at a 20 fold higher IgG concentration. It will not neutralize the biological activity of rmMIP-1▀ or rmMIP-1 alpha .
gene symbol :
CCL3
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Chemotaxis Induced by CCL3/MIP-1a and Neutral-ization by Human CCL3/ MIP-1a Antibody.
accessionNumbers :
P10147
applications :
Immunohistochemistry,ELISA Capture (Matched Antibody Pair),Antibody Array Development,ELISA Development,Luminex Development,Flow Cytometry,Western Blot,Neutralization
USD :
539 USD
alt names :
C-C motif chemokine 3, MIP1-(a), AI323804, chemokine (C-C motif) ligand 3, G0S19-1, LD78a, LD78alpha, MIP1 alpha, MIP-1 alpha, Mip1a, MIP-1alpha, MIP1-alpha, PAT 464.1, SCYA3, SIS-beta
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.