HB-EGF Antibody | R&D Systems AF-259 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

HB-EGF Antibody

catalog :

AF-259

quantity :

25 ug

price :

129 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, neutralization

citations: 7

Reference
Miranda da Costa N, Saab Abe C, Mitre G, Mesquita R, Silva Kataoka M, Ribeiro Ribeiro A, et al. HIF-1α is Overexpressed in Odontogenic Keratocyst Suggesting Activation of HIF-1α and NOTCH1 Signaling Pathways. Cells. 2019;8: pubmed publisher
Branco D, da Costa N, Abe C, Kataoka M, Pinheiro J, Alves Júnior S. HIF-1α, NOTCH1, ADAM12, and HB-EGF are overexpressed in mucoepidermoid carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019;127:e8-e17 pubmed publisher
Stevens M, Neal C, Salmon A, Bates D, Harper S, Oltean S. Vascular Endothelial Growth Factor-A165b Restores Normal Glomerular Water Permeability in a Diphtheria-Toxin Mouse Model of Glomerular Injury. Nephron. 2018;139:51-62 pubmed publisher
Carroll M, Kapur A, Felder M, Patankar M, Kreeger P. M2 macrophages induce ovarian cancer cell proliferation via a heparin binding epidermal growth factor/matrix metalloproteinase 9 intercellular feedback loop. Oncotarget. 2016;7:86608-86620 pubmed publisher
Veltmann M, Hollborn M, Reichenbach A, Wiedemann P, Kohen L, Bringmann A. Osmotic Induction of Angiogenic Growth Factor Expression in Human Retinal Pigment Epithelial Cells. PLoS ONE. 2016;11:e0147312 pubmed publisher
Li D, Wang A, Liu X, Meisgen F, GrÃ¼nler J, Botusan I, et al. MicroRNA-132 enhances transition from inflammation to proliferation during wound healing. J Clin Invest. 2015;125:3008-26 pubmed publisher
Yu V, Saez B, Cook C, Lotinun S, Pardo Saganta A, Wang Y, et al. Specific bone cells produce DLL4 to generate thymus-seeding progenitors from bone marrow. J Exp Med. 2015;212:759-74 pubmed publisher

product information

brand :

R&D Systems

SKU :

AF-259

product name :

HB-EGF Antibody

unit sizes :

25 ug

description :

The Human HB-EGF Antibody from R&D Systems is a goat polyclonal antibody to HB-EGF. This antibody reacts with human. The Human HB-EGF Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Neutralization, ELISA Capture (Matched Antibody Pair).

target :

HB-EGF

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human HB-EGF (R D Systems, Catalog # 259-HE), Asp63-Leu148, Accession # Q99075

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human

specificity :

Detects human HB-EGF in ELISAs and Western blots. In direct ELISAs, less than 1% cross reactivity with recombinant mouse HB-EGF is observed. In sandwich immunoassays, less than 0.1% cross-reactivity with recombinant human (rh) Amphiregulin, rhBetacellulin, rhEpiregulin, and recombinant mouse Epigen is observed.

gene symbol :

HBEGF

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

AF-259-NA

accessionNumbers :

Q99075

applications :

Western Blot, Immunohistochemistry, Neutralization, ELISA Capture (Matched Antibody Pair)

USD :

129 USD

applications abr :

WB, IHC, Neut, ELISA(Cap)

alt names :

diphtheria toxin receptor (heparin-binding epidermal growth factor-like growthfactor), Dtr, DTRHEGFLdiphtheria toxin receptor (heparin-binding EGF-like growth factor), Dts, DTSF, HBEGF, Hegfl, heparin-binding EGF-like growth factor, heparin-binding epidermal growth factor, proheparin-binding EGF-like growth factor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.