Human TGF┐▀ RIII Antibody | R&D Systems AF-242-PB product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human TGF┐▀ RIII Antibody

catalog :

AF-242-PB

quantity :

250 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, immunohistochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; human; loading ...; fig 5a western blot; human; loading ...; fig 1b	JENKINS L, Singh P, Varadaraj A, Lee N, Shah S, Flores H, et al. Altering the Proteoglycan State of Transforming Growth Factor ? Type III Receptor (T?RIII)/Betaglycan Modulates Canonical Wnt/?-Catenin Signaling. J Biol Chem. 2016;291:25716-25728 pubmed
western blot; human; loading ...; fig 5b	Bekhouche M, Leduc C, Dupont L, Janssen L, Delolme F, Vadon Le Goff S, et al. Determination of the substrate repertoire of ADAMTS2, 3, and 14 significantly broadens their functions and identifies extracellular matrix organization and TGF-Î² signaling as primary targets. FASEB J. 2016;30:1741-56 pubmed publisher
	Tazat K, Pomeraniec Abudy L, Hector Greene M, Szilágyi S, Sharma S, Cai E, et al. ALK1 regulates the internalization of endoglin and the type III TGF-β receptor. Mol Biol Cell. 2021;32:605-621 pubmed publisher
	Facciotti F, Larghi P, Bosotti R, Vasco C, Gagliani N, Cordiglieri C, et al. Evidence for a pathogenic role of extrafollicular, IL-10-producing CCR6+B helper T cells in systemic lupus erythematosus. Proc Natl Acad Sci U S A. 2020;117:7305-7316 pubmed publisher
	Drasin D, Guarnieri A, Neelakantan D, Kim J, Cabrera J, Wang C, et al. TWIST1-Induced miR-424 Reversibly Drives Mesenchymal Programming while Inhibiting Tumor Initiation. Cancer Res. 2015;75:1908-21 pubmed publisher

product information

master code :

AF-242-PB

SKU :

AF-242-PB

product name :

Human TGF┐▀ RIII Antibody

unit size :

250 ug (also 25 ug)

description :

The Human TGF¿ß RIII Antibody from R&D Systems is a goat polyclonal antibody to TGF-beta RIII. This antibody reacts with human,primate - chlorocebus aethiops (african green monkey),rabbit,rat. The Human TGF¿ß RIII Antibody has been validated for the following applications: Western Blot,ELISA Development,Flow Cytometry,Immunoprecipitation,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,CyTOF-ready.

target :

TGF-beta RIII

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human TGF┐▀ RIII, Gly21-Asp781, Accession # AAA67061

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Rabbit,Rat

specificity :

Detects human TGF┐▀ RIII in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant mouse (rm) TGF┐▀ RIII is observed, and less than 1% cross-reactivity with recombinant human (rh) TGF┐▀ RI, rhTGF┐▀ RII, rhTGF┐▀ RIIB, and rmTGF┐▀ RI is observed.

gene symbol :

TGFBR3

top caption :

TGF-beta RIII antibody in Human Placenta Tissue by Immunohistochemistry (IHC-P).

accessionNumbers :

AAA67061

applications :

ELISA Development,Flow Cytometry,Immunoprecipitation,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,CyTOF-ready

USD :

509 USD

alt names :

betaglycan, betaglycan proteoglycan, BGCAN, TBRIII, TGF-beta receptor type 3, TGF-beta receptor type III, TGFbetaRIII, TGFBR3, TGF-bRIII, TGFR-3, Transforming growth factor beta receptor III, transforming growth factor beta receptor type 3, transforming growth factor, beta receptor III, transforming growth factor, beta receptor III (betaglycan, 300kDa)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage