product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human PDGF-BB Antibody
catalog :
AF-220-NA
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section, dot blot
more info or order :
citations: 8
Reference
Saddouk F, Kuzemczak A, Saito J, Greif D. Endothelial HIFα/PDGF-B to smooth muscle Beclin1 signaling sustains pathological muscularization in pulmonary hypertension. JCI Insight. 2024;9: pubmed publisher
Li J, Chen X, Ren L, Chen X, Wu T, Wang Y, et al. Type H vessel/platelet-derived growth factor receptor β+ perivascular cell disintegration is involved in vascular injury and bone loss in radiation-induced bone damage. Cell Prolif. 2023;56:e13406 pubmed publisher
Li X, Lee E, Lilja S, Loscalzo J, Sch xe4 fer S, Smelik M, et al. A dynamic single cell-based framework for digital twins to prioritize disease genes and drug targets. Genome Med. 2022;14:48 pubmed publisher
Annarapu G, Nolfi Donegan D, Reynolds M, Wang Y, Kohut L, Zuckerbraun B, et al. Heme stimulates platelet mitochondrial oxidant production to induce targeted granule secretion. Redox Biol. 2021;48:102205 pubmed publisher
Beckmann R, Jensen K, Fenn S, Speck J, Krause K, Meier A, et al. DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously. Nat Commun. 2021;12:708 pubmed publisher
Huang J, Yin H, Rao S, Xie P, Cao X, Rao T, et al. Harmine enhances type H vessel formation and prevents bone loss in ovariectomized mice. Theranostics. 2018;8:2435-2446 pubmed publisher
Ueno K, Takeuchi Y, Samura M, Tanaka Y, Nakamura T, Nishimoto A, et al. Treatment of refractory cutaneous ulcers with mixed sheets consisting of peripheral blood mononuclear cells and fibroblasts. Sci Rep. 2016;6:28538 pubmed publisher
Gao Y, Zhou Z, Lu S, Huang X, Zhang C, Jiang R, et al. Chemokine CCL15 Mediates Migration of Human Bone Marrow-Derived Mesenchymal Stem Cells Toward Hepatocellular Carcinoma. Stem Cells. 2016;34:1112-22 pubmed publisher
product information
brand :
R&D Systems
master code :
AF-220-NA
SKU :
AF-220-NA
product name :
Human PDGF-BB Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human PDGF-BB Antibody from R&D Systems is a goat polyclonal antibody to PDGF-BB. This antibody reacts with human,mouse,rabbit,rat. The Human PDGF-BB Antibody has been validated for the following applications: Neutralization,Western Blot,Dot Blot,ELISA Detection,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry.
target :
PDGF-BB
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.1 ug/mL, Neutralization 0.1-0.5 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant human PDGF-BB, Ser82-Thr190, Accession # P01127
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rabbit,Rat
specificity :
Detects PDGF-BB in direct ELISAs and Western blots.
gene symbol :
PDGFB
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Cell Proliferation Induced by PDGF-BB and Neutralization by Human PDGF-BB Antibody.
accessionNumbers :
P01127
applications :
Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Dot Blot,Neutralization,Immunocytochemistry,ELISA Detection
USD :
499 USD
alt names :
c-sis;IBGC5;PDGF2;PDGF-2;PDGFB;Platelet-derived growth factor subunit B;SIS;SSV, PDGFAB, PDGFBB
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.