Human/Rat GDNF Antibody | R&D Systems AF-212-NA product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Rat GDNF Antibody

catalog :

AF-212-NA

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, chicken, rhesus macaque

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 14

Reference
Ford M, George B, Van Laar V, Holleran K, Naidoo J, Hadaczek P, et al. GDNF gene therapy for alcohol use disorder in male non-human primates. Nat Med. 2023;29:2030-2040 pubmed publisher
Saito Y, Miyajima M, Yamamoto S, Miura N, Sato T, Kita A, et al. Intrathecal Injection of Mesenchymal Stromal Cell Cultured on 3D Fiber Ameliorates Multiple Organ Damage in Murine Lupus. Stem Cells Transl Med. 2022;11:644-658 pubmed publisher
Sultan N, Scheven B. Exploring the potential application of dental pulp stem cells in neuroregenerative medicine. Neural Regen Res. 2022;17:775-776 pubmed publisher
Sultan N, Amin L, Zaher A, Grawish M, Scheven B. Dental pulp stem cells stimulate neuronal differentiation of PC12 cells. Neural Regen Res. 2021;16:1821-1828 pubmed publisher
Yin J, Chang H, Yi Y, Yao Y, Leung P. TGF-β1 Increases GDNF Production by Upregulating the Expression of GDNF and Furin in Human Granulosa-Lutein Cells. Cells. 2020;9: pubmed publisher
Sonne J, Groshong J, Seavey C, Gash D. Spatial and temporal immunoreactivity in the rat brain using an affinity purified polyclonal antibody to DNSP-11. J Chem Neuroanat. 2019;100:101664 pubmed publisher
Nakasatomi M, Takahashi S, Sakairi T, Ikeuchi H, Kaneko Y, Hiromura K, et al. Enhancement of HGF-induced tubulogenesis by endothelial cell-derived GDNF. PLoS ONE. 2019;14:e0212991 pubmed publisher
Quintino L, Namislo A, Davidsson M, Breger L, Kavanagh P, Avallone M, et al. Destabilizing Domains Enable Long-Term and Inert Regulation of GDNF Expression in the Brain. Mol Ther Methods Clin Dev. 2018;11:29-39 pubmed publisher
Jalili R, Horecka J, Swartz J, Davis R, Persson H. Streamlined circular proximity ligation assay provides high stringency and compatibility with low-affinity antibodies. Proc Natl Acad Sci U S A. 2018;115:E925-E933 pubmed publisher
Nagashima K, Miwa T, Soumiya H, Ushiro D, Takeda Kawaguchi T, Tamaoki N, et al. Priming with FGF2 stimulates human dental pulp cells to promote axonal regeneration and locomotor function recovery after spinal cord injury. Sci Rep. 2017;7:13500 pubmed publisher
Lavaur J, Le Nogue D, Lemaire M, Pype J, Farjot G, Hirsch E, et al. The noble gas xenon provides protection and trophic stimulation to midbrain dopamine neurons. J Neurochem. 2017;142:14-28 pubmed publisher
Dong Y, Kanda A, Noda K, Saito W, Ishida S. Pathologic Roles of Receptor-Associated Prorenin System in Idiopathic Epiretinal Membrane. Sci Rep. 2017;7:44266 pubmed publisher
Thomsen G, Alkaslasi M, Vit J, Lawless G, Godoy M, Gowing G, et al. Systemic injection of AAV9-GDNF provides modest functional improvements in the SOD1G93A ALS rat but has adverse side effects. Gene Ther. 2017;24:245-252 pubmed publisher
Stott S, Hayat S, Carnwath T, Garas S, Sleeman J, Barker R. CD24 expression does not affect dopamine neuronal survival in a mouse model of Parkinson's disease. PLoS ONE. 2017;12:e0171748 pubmed publisher

product information

brand :

R&D Systems

master code :

AF-212-NA

SKU :

AF-212-NA

product name :

Human/Rat GDNF Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human/Rat GDNF Antibody from R&D Systems is a goat polyclonal antibody to GDNF. This antibody reacts with avian - chicken,human,mouse,n/a,primate - callithrix jacchus (common marmoset),primate - macaca mulatta (rhesus macaque),rat. The Human/Rat GDNF Antibody has been validated for the following applications: Neutralization,Affinity Assay,ELISA Development (Detection),Flow Cytometry,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry.

target :

GDNF

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Immunohistochemistry 5-15 ug/mL, Neutralization 0.25-1 ug/mL

host :

Goat

immunogen :

E. coli -derived and Mouse myeloma cell line NS0-derived recombinant human GDNF, Arg109-Ile211, Accession # P39905

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Avian - Chicken,Human,Mouse,N/A,Primate - Callithrix jacchus (Common Marmoset),Primate - Macaca mulatta (Rhesus Macaque),Rat

specificity :

Detects human and rat GDNF in direct ELISAs and Western blots.

gene symbol :

GDNF

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

GDNF and GFRa-1 antibody in Rat Dorsal Root Ganglia by Immunohistochemistry (IHC-Fr).

accessionNumbers :

P39905

applications :

Affinity Assay,ELISA Development (Detection),Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry

USD :

489 USD

alt names :

Astrocyte-derived trophic factor, ATF, ATF1, ATF2, glial cell derived neurotrophic factor, glial cell line derived neurotrophic factor, glial cell line-derived neurotrophic factor, HFB1-GDNF, HGDNF, HSCR3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage