product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human TNF-alpha Antibody
catalog :
AF-210-NA
quantity :
100 ug (also 25 ug)
price :
509 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, blocking or activating experiments
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; human; loading ...; fig s2a
Guicciardi M, Krishnan A, Bronk S, Hirsova P, Griffith T, Gores G. Biliary tract instillation of a SMAC mimetic induces TRAIL-dependent acute sclerosing cholangitis-like injury in mice. Cell Death Dis. 2017;8:e2535 pubmed publisher
  • blocking or activating experiments; human; loading ...; fig 4
Savill S, Leitch H, Harvey J, Thomas T. Inflammatory Adipokines Decrease Expression of Two High Molecular Weight Isoforms of Tropomyosin Similar to the Change in Type 2 Diabetic Patients. PLoS ONE. 2016;11:e0162908 pubmed publisher
Chandrasekharan U, Kaur R, Harvey J, Braley C, Rai V, Lee M, et al. TNFR2 Depletion Reduces Psoriatic Inflammation in Mice by Downregulating Specific Dendritic Cell Populations in Lymph Nodes and Inhibiting IL-23/IL-17 Pathways. J Invest Dermatol. 2022;142:2159-2172.e9 pubmed publisher
Pokrovskaya I, Yadav S, Rao A, McBride E, Kamykowski J, Zhang G, et al. 3D ultrastructural analysis of α-granule, dense granule, mitochondria, and canalicular system arrangement in resting human platelets. Res Pract Thromb Haemost. 2020;4:72-85 pubmed publisher
Ni K, Gill A, Cao D, Koike K, Schweitzer K, Garantziotis S, et al. Intravascular heavy chain-modification of hyaluronan during endotoxic shock. Biochem Biophys Rep. 2019;17:114-121 pubmed publisher
Kim M, Pyo S, Kang C, Lee C, Lee H, Choi S, et al. Folate receptor 1 (FOLR1) targeted chimeric antigen receptor (CAR) T cells for the treatment of gastric cancer. PLoS ONE. 2018;13:e0198347 pubmed publisher
Rothhammer V, Borucki D, Kenison J, Hewson P, Wang Z, Bakshi R, et al. Detection of aryl hydrocarbon receptor agonists in human samples. Sci Rep. 2018;8:4970 pubmed publisher
Jalili R, Horecka J, Swartz J, Davis R, Persson H. Streamlined circular proximity ligation assay provides high stringency and compatibility with low-affinity antibodies. Proc Natl Acad Sci U S A. 2018;115:E925-E933 pubmed publisher
Rochat M, Schlaepfer E, Speck R. Promising Role of Toll-Like Receptor 8 Agonist in Concert with Prostratin for Activation of Silent HIV. J Virol. 2017;91: pubmed publisher
product information
master code :
AF-210-NA
SKU :
AF-210-NA
product name :
Human TNF-alpha Antibody
unit size :
100 ug (also 25 ug)
description :
The Human TNF-alpha Antibody from R&D Systems is a goat polyclonal antibody to TNF-alpha. This antibody reacts with human,mouse,primate - papio cynocephalus (yellow baboon). The Human TNF-alpha Antibody has been validated for the following applications: Immunohistochemistry,Neutralization,Western Blot,Affinity Assay,Bioassay,ELISA Development,Functional Assay,Immunocytochemistry.
target :
TNF-alpha
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant human TNF-alpha , Val77-Leu233, Accession # P01375
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Primate - Papio cynocephalus (Yellow Baboon)
specificity :
Detects human TNF-alpha in direct ELISAs and Western blots.
gene symbol :
TNF
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Cytotoxicity Induced by TNF-a and Neutralization by Human TNF-a Antibody.
accessionNumbers :
P01375
applications :
Western Blot,Neutralization,Affinity Assay,Bioassay,ELISA Development,Functional Assay,Immunohistochemistry,Immunocytochemistry
USD :
509 USD
alt names :
APC1 protein, Cachectin, Cachetin, DIF, TNF, TNF, monocyte-derived, TNF-a, TNFA, TNFalpha, TNF-alphacachectin, TNFATNF, macrophage-derived, TNFG1F, TNFSF1A, TNFSF2, TNFSF2TNF superfamily, member 2, tumor necrosis factor, tumor necrosis factor (TNF superfamily, member 2), tumor necrosis factor alpha, Tumor necrosis factor ligand superfamily member 2, tumor necrosis factor-alpha
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.