product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human IL-8/CXCL8 Antibody
catalog :
AF-208-NA
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, rhesus macaque
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section
more info or order :
citations: 8
Reference
Franco Y, de Moraes M, Carvalho L, Dohle W, da Silva R, Noma I, et al. 2-Methoxyestradiol-3,17-O,O-bis-sulfamate (STX140) Inhibits Proliferation and Invasion via Senescence Pathway Induction in Human BRAFi-Resistant Melanoma Cells. Int J Mol Sci. 2023;24: pubmed publisher
Zhang Z, Ju C, Wu L, Yan H, Hong W, Chen H, et al. Therapeutic potency of compound RMY-205 for pulmonary fibrosis induced by SARS-CoV-2 nucleocapsid protein. Cell Chem Biol. 2023;30:261-277.e8 pubmed publisher
Xiong H, Ye J, Xie K, Hu W, Xu N, Yang H. Exosomal IL-8 derived from Lung Cancer and Colon Cancer cells induced adipocyte atrophy via NF-κB signaling pathway. Lipids Health Dis. 2022;21:147 pubmed publisher
Piao H, Fu L, Wang Y, Liu Y, Wang Y, Meng X, et al. A positive feedback loop between gastric cancer cells and tumor-associated macrophage induces malignancy progression. J Exp Clin Cancer Res. 2022;41:174 pubmed publisher
Wallis R, Josipovic N, Mizen H, Robles Tenorio A, Tyler E, Papantonis A, et al. Isolation methodology is essential to the evaluation of the extracellular vesicle component of the senescence-associated secretory phenotype. J Extracell Vesicles. 2021;10:e12041 pubmed publisher
Ortiz Montero P, Londono Vallejo A, Vernot J. Senescence-associated IL-6 and IL-8 cytokines induce a self- and cross-reinforced senescence/inflammatory milieu strengthening tumorigenic capabilities in the MCF-7 breast cancer cell line. Cell Commun Signal. 2017;15:17 pubmed publisher
Siew L, Wu S, Ying S, Corrigan C. Cigarette smoking increases bronchial mucosal IL-17A expression in asthmatics, which acts in concert with environmental aeroallergens to engender neutrophilic inflammation. Clin Exp Allergy. 2017;47:740-750 pubmed publisher
Ahn S, Park H, Ahn Y, Kim S, Cho M, Kang J, et al. Necrotic cells influence migration and invasion of glioblastoma via NF-?B/AP-1-mediated IL-8 regulation. Sci Rep. 2016;6:24552 pubmed publisher
product information
brand :
R&D Systems
master code :
AF-208-NA
SKU :
AF-208-NA
product name :
Human IL-8/CXCL8 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human IL-8/CXCL8 Antibody from R&D Systems is a goat polyclonal antibody to CXCL8/IL-8. This antibody reacts with human,mouse,primate - macaca mulatta (rhesus macaque). The Human IL-8/CXCL8 Antibody has been validated for the following applications: Immunohistochemistry,ELISA Development,Western Blot,Neutralization,Immunohistochemistry-Paraffin,In vivo assay,Simple Western,Immunocytochemistry.
target :
IL-8/CXCL8
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 2 ug/mL, Simple Western 25 ug/mL, Immunohistochemistry 5-15 ug/mL, Neutralization 0.1-0.5 ug/mL, Immunocytochemistry 5-15 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant human IL-8/CXCL8, Ser28-Ser99, Accession # P10145
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Primate - Macaca mulatta (Rhesus Macaque)
specificity :
Detects human IL-8/CXCL8 in direct ELISAs and Western blots.
gene symbol :
IL8
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
accessionNumbers :
P10145
applications :
Simple Western,Immunocytochemistry,ELISA Development,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,In vivo assay,Neutralization
USD :
489 USD
alt names :
3-10C, AMCF-I, C-X-C motif chemokine 8, CXCL8, CXCL8SCYB8, Emoctakin, GCP1, GCP-1TSG-1, IL8, interleukin 8, K60, LAI, LECT, LUCT, LYNAP, MDNCF, MDNCFb-ENAP, member 8, MONAP, MONAPGCP1, NAF, NAP1, NAP-1NAP1, NCF, Neutrophil-activating protein 1, Protein 3-10C, T cell chemotactic factor, T-cell chemotactic factor, TCF, TSG1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.