Human IL-1 alpha /IL-1F1 Antibody | R&D Systems AF-200-NA product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-1 alpha /IL-1F1 Antibody

catalog :

AF-200-NA

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rhesus macaque

application :

western blot, ELISA, immunocytochemistry, neutralization, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 10

Reference
Cheng Y, Acedera J, Li Y, Shieh S. A keratinocyte-adipocyte signaling loop is reprogrammed by loss of BTG3 to augment skin carcinogenesis. Cell Death Differ. 2024;31:970-982 pubmed publisher
Smer Barreto V, Quintanilla A, Elliott R, Dawson J, Sun J, Campa V, et al. Discovery of senolytics using machine learning. Nat Commun. 2023;14:3445 pubmed publisher
Zhao M, Zhang L, Sun Z, Qiao L, Yang T, Ren Y, et al. A novel microRNA-182/Interleukin-8 regulatory axis controls osteolytic bone metastasis of lung cancer. Cell Death Dis. 2023;14:298 pubmed publisher
Chao Y, Puhach A, Frieser D, Arunkumar M, Lehner L, Seeholzer T, et al. Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation. Nat Immunol. 2023;24:295-308 pubmed publisher
Zhu H, Chan K, Huang X, Cerra C, Blake S, Trigos A, et al. Cystathionine-β-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation. elife. 2022;11: pubmed publisher
Pan Z, Gao Y, Liu S, Ke Z, Guo J, Ma W, et al. Wu-Zi-Yan-Zong-Wan protects mouse blood-testis barrier from Tripterygium wilfordii Hook. f. multiglycoside-induced disruption by regulating proinflammatory cytokines. J Ethnopharmacol. 2021;280:114440 pubmed publisher
Liu D, Steins A, Klaassen R, van der Zalm A, Bennink R, van Tienhoven G, et al. Soluble Compounds Released by Hypoxic Stroma Confer Invasive Properties to Pancreatic Ductal Adenocarcinoma. Biomedicines. 2020;8: pubmed publisher
Sun J, LaRock D, Skowronski E, Kimmey J, Olson J, Jiang Z, et al. The Pseudomonas aeruginosa protease LasB directly activates IL-1β. EBioMedicine. 2020;60:102984 pubmed publisher
Qiang L, Sample A, Shea C, Soltani K, Macleod K, He Y. Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis. Autophagy. 2017;: pubmed publisher
Savill S, Leitch H, Harvey J, Thomas T. Inflammatory Adipokines Decrease Expression of Two High Molecular Weight Isoforms of Tropomyosin Similar to the Change in Type 2 Diabetic Patients. PLoS ONE. 2016;11:e0162908 pubmed publisher

product information

brand :

R&D Systems

master code :

AF-200-NA

SKU :

AF-200-NA

product name :

Human IL-1 alpha /IL-1F1 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human IL-1 alpha /IL-1F1 Antibody from R&D Systems is a goat polyclonal antibody to IL-1 alpha/IL-1F1. This antibody reacts with human,mouse,primate - macaca mulatta (rhesus macaque). The Human IL-1 alpha /IL-1F1 Antibody has been validated for the following applications: Neutralization,Bioassay,Inhibition,Western Blot,ELISA Capture,Immunohistochemistry-Paraffin,Immunocytochemistry.

target :

IL-1 alpha/IL-1F1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Neutralization 4-20 ng/mL, Immunocytochemistry 5-15 ug/mL

host :

Goat

immunogen :

E. coli -derived recombinant human IL-1 alpha /IL-1F1, Ser113-Ala271, Accession # Q53QF9

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Primate - Macaca mulatta (Rhesus Macaque)

specificity :

Detects human IL-1 alpha /IL-1F1 in direct ELISAs and Western blots.

gene symbol :

IL1A

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced by IL-1a/IL-1F1 and Neutralization by Human IL-1a/IL-1F1 Antibody.

accessionNumbers :

Q53QF9

applications :

Bioassay,Inhibition,Western Blot,Immunohistochemistry-Paraffin,Neutralization,Immunocytochemistry,ELISA Capture

USD :

509 USD

alt names :

BAF, Hematopoietin-1, IL1, IL1 alpha, IL-1 alpha, IL1A, IL-1A, IL1-ALPHA, IL1F1, IL-1F1, IL1F1hematopoietin-1, interleukin 1, alpha, interleukin-1 alpha, LAF, LEM, preinterleukin 1 alpha, pro-interleukin-1-alpha

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage