Human B7-2/CD86 Antibody | R&D Systems AF-141-NA product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human B7-2/CD86 Antibody

catalog :

AF-141-NA

quantity :

200 ug (also 25 ug)

price :

399 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 6

Reference
Popugailo A, Rotfogel Z, Levy M, Turgeman O, Hillman D, Levy R, et al. The homodimer interfaces of costimulatory receptors B7 and CD28 control their engagement and pro-inflammatory signaling. J Biomed Sci. 2023;30:49 pubmed publisher
Horiba S, Kami R, Tsutsui T, Hosoi J. IL-34 Downregulation‒Associated M1/M2 Macrophage Imbalance Is Related to Inflammaging in Sun-Exposed Human Skin. JID Innov. 2022;2:100112 pubmed publisher
Zrzavy T, Hoftberger R, Berger T, Rauschka H, Butovsky O, Weiner H, et al. Pro-inflammatory activation of microglia in the brain of patients with sepsis. Neuropathol Appl Neurobiol. 2019;45:278-290 pubmed publisher
Ai P, Li Z, Jiang Y, Song C, Zhang L, Hu H, et al. Tumor microenvironment contributes to Epstein-Barr virus anti-nuclear antigen-1 antibody production in nasopharyngeal carcinoma. Oncol Lett. 2017;14:2458-2462 pubmed publisher
Zrzavy T, Hametner S, Wimmer I, Butovsky O, Weiner H, Lassmann H. Loss of 'homeostatic' microglia and patterns of their activation in active multiple sclerosis. Brain. 2017;140:1900-1913 pubmed publisher
Dal Bianco A, Grabner G, Kronnerwetter C, Weber M, Hoftberger R, Berger T, et al. Slow expansion of multiple sclerosis iron rim lesions: pathology and 7 T magnetic resonance imaging. Acta Neuropathol. 2017;133:25-42 pubmed publisher

product information

master code :

AF-141-NA

SKU :

AF-141-NA

product name :

Human B7-2/CD86 Antibody

unit size :

200 ug (also 25 ug)

description :

The Human B7-2/CD86 Antibody from R&D Systems is a goat polyclonal antibody to B7-2/CD86. This antibody reacts with human,mouse. The Human B7-2/CD86 Antibody has been validated for the following applications: Immunohistochemistry,ELISA Development,Flow Cytometry,Immunohistochemistry-Paraffin,Western Blot,Neutralization,Knockout Validated.

target :

B7-2/CD86

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human B7-2/CD86, Ala23-His244, Accession # P42081

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects human B7-2/CD86 in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant mouse B7-2 and recombinant rat B7-2 is observed.

gene symbol :

CD86

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

Antibody validation :

Knockout/Knockdown

top caption :

Detection of Human B7-2/CD86 antibody by Western Blot.

accessionNumbers :

P42081

applications :

Immunohistochemistry,ELISA Development,Flow Cytometry,Immunohistochemistry-Paraffin,Western Blot,Neutralization,Knockout Validated

USD :

399 USD

alt names :

Activation B7-2 antigen, B70, B72, B7-2, B7-2 antigen, B-lymphocyte activation antigen B7-2, BU63, CD28 antigen ligand 2, CD28LG2B7-2 antigen), CD86, CD86 antigen, CD86 molecule, CTLA-4 counter-receptor B7.2, FUN-1, LAB72, MGC34413, T-lymphocyte activation antigen CD86

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage