product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human VCAM-1/CD106 Protein, CF
catalog :
ADP5-050
quantity :
50 ug (also 200 ug)
price :
385 USD
more info or order :
citations: 9
Reference
Naci D, Berrazouane S, Barabé F, Aoudjit F. Cell adhesion to collagen promotes leukemia resistance to doxorubicin by reducing DNA damage through the inhibition of Rac1 activation. Sci Rep. 2019;9:19455 pubmed publisher
Caccuri F, Bugatti A, Corbellini S, Roversi S, Zani A, Mazzuca P, et al. The Synthetic Dipeptide Pidotimod Shows a Chemokine-Like Activity through CXC Chemokine Receptor 3 (CXCR3). Int J Mol Sci. 2019;20: pubmed publisher
Pepin M, Mezouar S, Pegon J, Muczynski V, Adam F, Bianchini E, et al. Soluble Siglec-5 associates to PSGL-1 and displays anti-inflammatory activity. Sci Rep. 2016;6:37953 pubmed publisher
Bailon E, Ugarte Berzal E, Amigo Jiménez I, Van den Steen P, Opdenakker G, Garcia Marco J, et al. Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen. J Leukoc Biol. 2014;96:185-99 pubmed publisher
Ugarte Berzal E, Bailon E, Amigo Jiménez I, Albar J, Garcia Marco J, Garcia Pardo A. A novel CD44-binding peptide from the pro-matrix metalloproteinase-9 hemopexin domain impairs adhesion and migration of chronic lymphocytic leukemia (CLL) cells. J Biol Chem. 2014;289:15340-9 pubmed publisher
Barkho B, Song H, Aimone J, Smrt R, Kuwabara T, Nakashima K, et al. Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation. Stem Cells Dev. 2006;15:407-21 pubmed
Brooks A, Bates M, Vrtis R, Jarjour N, Bertics P, Sedgwick J. Urokinase-type plasminogen activator modulates airway eosinophil adhesion in asthma. Am J Respir Cell Mol Biol. 2006;35:503-11 pubmed
Yamamoto H, Nagata M, Sakamoto Y. CC chemokines and transmigration of eosinophils in the presence of vascular cell adhesion molecule 1. Ann Allergy Asthma Immunol. 2005;94:292-300 pubmed
Levesque J, Liu F, Simmons P, Betsuyaku T, Senior R, Pham C, et al. Characterization of hematopoietic progenitor mobilization in protease-deficient mice. Blood. 2004;104:65-72 pubmed
product information
brand :
R&D Systems
master code :
ADP5
SKU :
ADP5-050
product name :
Recombinant Human VCAM-1/CD106 Protein, CF
unit size :
50 ug (also 200 ug)
seo description :
The Recombinant Human VCAM-1/CD106 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human VCAM-1/CD106 Protein, CF has been validated for the following applications: Bioactivity.
target :
VCAM-1/CD106
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS containing Calcium and Magnesium with Sorbitol.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
93-95 kDa, reducing conditions
theoretical molecular weight :
74.1 kDa
gene symbol :
VCAM1
details of functionality :
Measured by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells. When 5 x 104 cells/well are added to human sVCAM-1 coated plates (10 ╡g/mL with 100 ╡L/well), 85% will adhere after 1 hour incubation at room temperature.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P19320-1
applications :
Bioactivity
source :
CHO-derived Recombinant Human VCAM-1/CD106 Protein, CF
USD :
385 USD
alt names :
CD106, CD106 antigen, DKFZp779G2333, INCAM-100, L1CAM, MGC99561, vascular cell adhesion molecule 1, vascular cell adhesion protein 1, V-CAM 1, VCAM1, VCAM-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.