Recombinant Human E-Selectin/CD62E Protein, CF | R&D Systems ADP1-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human E-Selectin/CD62E Protein, CF

catalog :

ADP1-050

quantity :

50 ug (also 200 ug)

price :

325 USD

more info or order :

R&D Systems product webpage

citations: 12

Reference
Wackerbarth L, Seifert S, Napoli M, Rohwedder I, Vogl T, Scheiermann C, et al. Neonatal neutrophils exhibit reduced NLRP3 inflammasome activation. J Leukoc Biol. 2025;117: pubmed publisher
Ortiz Otero N, Marshall J, Glenn A, Matloubieh J, Joseph J, Sahasrabudhe D, et al. TRAIL-coated leukocytes to kill circulating tumor cells in the flowing blood from prostate cancer patients. BMC Cancer. 2021;21:898 pubmed publisher
Terävä J, Tiainen L, Lamminmaki U, Kellokumpu Lehtinen P, Pettersson K, Gidwani K. Lectin nanoparticle assays for detecting breast cancer-associated glycovariants of cancer antigen 15-3 (CA15-3) in human plasma. PLoS ONE. 2019;14:e0219480 pubmed publisher
Myung J, Eblan M, Caster J, Park S, Poellmann M, Wang K, et al. Multivalent Binding and Biomimetic Cell Rolling Improves the Sensitivity and Specificity of Circulating Tumor Cell Capture. Clin Cancer Res. 2018;24:2539-2547 pubmed publisher
Saha A, Osmulski P, Dallo S, Gaczynska M, Huang T, Ramasubramanian A. Cholesterol Regulates Monocyte Rolling through CD44 Distribution. Biophys J. 2017;112:1481-1488 pubmed publisher
Kang S, Hasan N, Mann A, Zheng W, Zhao L, Morris L, et al. Blocking the adhesion cascade at the premetastatic niche for prevention of breast cancer metastasis. Mol Ther. 2015;23:1044-1054 pubmed publisher
Oliveira Ferrer L, Rosler K, Haustein V, Schroder C, Wicklein D, Maltseva D, et al. c-FOS suppresses ovarian cancer progression by changing adhesion. Br J Cancer. 2014;110:753-63 pubmed publisher
Sun J, Li Y, Graziani G, Filion L, Allan D. E-selectin mediated adhesion and migration of endothelial colony forming cells is enhanced by SDF-1?/CXCR4. PLoS ONE. 2013;8:e60890 pubmed publisher
Deban L, Russo R, Sironi M, Moalli F, Scanziani M, Zambelli V, et al. Regulation of leukocyte recruitment by the long pentraxin PTX3. Nat Immunol. 2010;11:328-34 pubmed publisher
Gonzalez R, Seurynck Servoss S, Crowley S, Brown M, Omenn G, Hayes D, et al. Development and validation of sandwich ELISA microarrays with minimal assay interference. J Proteome Res. 2008;7:2406-14 pubmed publisher
Aychek T, Miller K, Sagi Assif O, Levy Nissenbaum O, Israeli Amit M, Pasmanik Chor M, et al. E-selectin regulates gene expression in metastatic colorectal carcinoma cells and enhances HMGB1 release. Int J Cancer. 2008;123:1741-50 pubmed publisher
Armitage J, Lindsey N, Homer Vanniasinkam S. The role of endothelial cell reactive antibodies in peripheral arterial disease. Eur J Vasc Endovasc Surg. 2006;31:170-5 pubmed

product information

brand :

R&D Systems

master code :

ADP1

SKU :

ADP1-050

product name :

Recombinant Human E-Selectin/CD62E Protein, CF

unit size :

50 ug (also 200 ug)

seo description :

The Recombinant Human E-Selectin/CD62E Protein, CF from R&D Systems is derived from CHO. The Recombinant Human E-Selectin/CD62E Protein, CF has been validated for the following applications: Bioactivity.

target :

E-Selectin/CD62E

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS containing Calcium and Magnesium with Sorbitol.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

86-90 kDa, reducing conditions

theoretical molecular weight :

58.6 kDa

gene symbol :

SELE

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells. When 5 x 104 cells/well are added to human E-Selectin coated plates (2 ╡g/mL with 100 ╡L/well), 80% cells will adhere after 1 hour incubation at 37 ░C. Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P16581

applications :

Bioactivity

source :

CHO-derived Recombinant Human E-Selectin/CD62E Protein, CF

USD :

325 USD

alt names :

CD62 antigen-like family member E, CD62E, CD62E antigen, ELAM, ELAM1, ELAM-1, ELAM1E-selectin, endothelial adhesion molecule 1, Endothelial leukocyte adhesion molecule 1, ESEL, LECAM2, leukocyte endothelial cell adhesion molecule 2, Leukocyte-endothelial cell adhesion molecule 2, SELE, selectin E

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage