Mouse CCL2/JE/MCP-1 Antibody | R&D Systems AB-479-NA product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse CCL2/JE/MCP-1 Antibody

catalog :

AB-479-NA

quantity :

1 mg

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, neutralization, flow cytometry, blocking or activating experiments

more info or order :

R&D Systems product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; mouse; 30 ug/ml; loading ...; fig 6d	Goyette M, Elkholi I, Apcher C, Kuasne H, Rothlin C, Muller W, et al. Targeting Axl favors an antitumorigenic microenvironment that enhances immunotherapy responses by decreasing Hif-1α levels. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
	Takacs G, Kreiger C, Luo D, Tian G, Garcia J, Deleyrolle L, et al. Glioma-derived CCL2 and CCL7 mediate migration of immune suppressive CCR2+/CX3CR1+ M-MDSCs into the tumor microenvironment in a redundant manner. Front Immunol. 2022;13:993444 pubmed publisher
	Lee S, Yoon G, Lee S, Kwon Y, Moon H, Kim Y, et al. Immunological and Pathological Peculiarity of Severe Acute Respiratory Syndrome Coronavirus 2 Beta Variant. Microbiol Spectr. 2022;10:e0237122 pubmed publisher
	Kim H, Kim W, Shin H, Yoon H, Moon J, Lee E, et al. ROS-induced PADI2 downregulation accelerates cellular senescence via the stimulation of SASP production and NFκB activation. Cell Mol Life Sci. 2022;79:155 pubmed publisher
	Miyamoto T, Murakami R, Hamanishi J, Tanigaki K, Hosoe Y, Mise N, et al. B7-H3 Suppresses Antitumor Immunity via the CCL2-CCR2-M2 Macrophage Axis and Contributes to Ovarian Cancer Progression. Cancer Immunol Res. 2022;10:56-69 pubmed publisher
	Flores I, Welc S, Wehling Henricks M, Tidball J. Myeloid cell-mediated targeting of LIF to dystrophic muscle causes transient increases in muscle fiber lesions by disrupting the recruitment and dispersion of macrophages in muscle. Hum Mol Genet. 2021;31:189-206 pubmed publisher
	Liu X, Guo A, Tu Y, Li W, Li L, Liu W, et al. Fruquintinib inhibits VEGF/VEGFR2 axis of choroidal endothelial cells and M1-type macrophages to protect against mouse laser-induced choroidal neovascularization. Cell Death Dis. 2020;11:1016 pubmed publisher
	Ramírez Moreno I, Ibarra Sanchez A, Castillo Arellano J, Blank U, Gonzalez Espinosa C. Mast Cells Localize in Hypoxic Zones of Tumors and Secrete CCL-2 under Hypoxia through Activation of L-Type Calcium Channels. J Immunol. 2020;204:1056-1068 pubmed publisher
	Welc S, Flores I, Wehling Henricks M, Ramos J, Wang Y, Bertoni C, et al. Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy. Nat Commun. 2019;10:2788 pubmed publisher
	John B, Naczki C, Patel C, Ghoneum A, Qasem S, Salih Z, et al. Regulation of the bi-directional cross-talk between ovarian cancer cells and adipocytes by SPARC. Oncogene. 2019;38:4366-4383 pubmed publisher

product information

master code :

AB-479-NA

SKU :

AB-479-NA

product name :

Mouse CCL2/JE/MCP-1 Antibody

unit size :

1 mg

description :

The Mouse CCL2/JE/MCP-1 Antibody from R&D Systems is a goat polyclonal antibody to CCL2/JE/MCP-1. This antibody reacts with human,mouse,transgenic mouse. The Mouse CCL2/JE/MCP-1 Antibody has been validated for the following applications: Neutralization,Flow Cytometry,Cell Culture,Immunohistochemistry,Western Blot.

target :

CCL2/JE/MCP-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant mouse CCL2/JE/MCP-1, Gln24-Arg96, Accession # Q5SVU3

isotype :

IgG

purity :

Protein A or G purified

species :

Human,Mouse,Transgenic Mouse

specificity :

Detects mouse CCL2/JE/MCP-1 in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human MCP-1, recombinant mouse (rm MCP-5, and recombinant rat JE is observed. In Western blots, no cross-reactivity with rmEotaxin, rmMCP-5, or rmCCL7 is observed.

gene symbol :

Ccl2

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Recombinant Mouse CCL2/JE/MCP-1 antibody by Western Blot.

accessionNumbers :

Q5SVU3

applications :

Neutralization,Flow Cytometry,Cell Culture,Immunohistochemistry,Western Blot

USD :

509 USD

alt names :

C-C motif chemokine ligand 2, CCL2, GDCF-2, HC11, HSMCR30, MCAF, Mcp1, MCP-1, SCYA2, SMC-CF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage