product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse LIF Antibody
catalog :
AB-449-NA
quantity :
1 mg
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, immunohistochemistry, neutralization, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 11
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 4a
Lee J, Hur J, Kwon Y, Chae C, Choi J, Hwang I, et al. KAI1(CD82) is a key molecule to control angiogenesis and switch angiogenic milieu to quiescent state. J Hematol Oncol. 2021;14:148 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 4d
Ma L, Zhao X, Liu Y, Wu J, Yang X, Jin Q. Dihydroartemisinin attenuates osteoarthritis by inhibiting abnormal bone remodeling and angiogenesis in subchondral bone. Int J Mol Med. 2021;47: pubmed publisher
Kakae M, Nakajima H, Tobori S, Kawashita A, Miyanohara J, Morishima M, et al. The astrocytic TRPA1 channel mediates an intrinsic protective response to vascular cognitive impairment via LIF production. Sci Adv. 2023;9:eadh0102 pubmed publisher
Xu S, Yang X, Chen Q, Liu Z, Chen Y, Yao X, et al. Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis. EBioMedicine. 2022;86:104312 pubmed publisher
Cai W, Shi L, Zhao J, Xu F, Dufort C, Ye Q, et al. Neuroprotection against ischemic stroke requires a specific class of early responder T cells in mice. J Clin Invest. 2022;132: pubmed publisher
Du J, Yang J, He Z, Cui J, Yang Y, Xu M, et al. Osteoblast and Osteoclast Activity Affect Bone Remodeling Upon Regulation by Mechanical Loading-Induced Leukemia Inhibitory Factor Expression in Osteocytes. Front Mol Biosci. 2020;7:585056 pubmed publisher
Skelly D, Czechanski A, Byers C, Aydin S, Spruce C, Olivier C, et al. Mapping the Effects of Genetic Variation on Chromatin State and Gene Expression Reveals Loci That Control Ground State Pluripotency. Cell Stem Cell. 2020;27:459-469.e8 pubmed publisher
Koide M, Yamashita T, Murakami K, Uehara S, Nakamura K, Nakamura M, et al. Sclerostin expression in trabecular bone is downregulated by osteoclasts. Sci Rep. 2020;10:13751 pubmed publisher
Welc S, Flores I, Wehling Henricks M, Ramos J, Wang Y, Bertoni C, et al. Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy. Nat Commun. 2019;10:2788 pubmed publisher
Arora G, Gupta A, Narayanan S, Guo T, Iyengar P, Infante R. Cachexia-associated adipose loss induced by tumor-secreted leukemia inhibitory factor is counterbalanced by decreased leptin. JCI Insight. 2018;3: pubmed publisher
Laresgoiti U, Nikolić M, Rao C, Brady J, Richardson R, Batchen E, et al. Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development. 2016;143:3686-3699 pubmed
product information
master code :
AB-449-NA
SKU :
AB-449-NA
product name :
Mouse LIF Antibody
unit size :
1 mg
description :
The Mouse LIF Antibody from R&D Systems is a goat polyclonal antibody to LIF. This antibody reacts with mouse,transgenic mouse. The Mouse LIF Antibody has been validated for the following applications: Immunohistochemistry,Reference Standard,Western Blot,Neutralization,In vivo assay.
target :
LIF
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant mouse LIF
isotype :
IgG
purity :
Protein A or G purified
species :
Mouse,Transgenic Mouse
specificity :
Detects mouse LIF in direct ELISAs and Western blots. In direct ELISAs, approximately 20% cross-reactivity with recombinant human LIF is observed. Neutralizes the biological activity of recombinant mouse LIF and will also neutralize the biological activity of recombinant human LIF at a 10-fold higher IgG concentration.
gene symbol :
LIF
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
IL-6 Secretion Induced by LIF and Neutralization by Mouse LIF Antibody.
applications :
Reference Standard,Western Blot,Neutralization,Immunohistochemistry,In vivo assay
USD :
499 USD
alt names :
CDF, D factor, DIA, differentiation inhibitory activity, differentiation stimulating factor, Differentiation-stimulating factor, Emfilermin, HILDA, HILDAcholinergic differentiation factor, leukemia inhibitory factor, leukemia inhibitory factor (cholinergic differentiation factor), Melanoma-derived LPL inhibitor, MLPLI
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.