Mouse TNF-alpha Antibody | R&D Systems AB-410-NA product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse TNF-alpha Antibody

catalog :

AB-410-NA

quantity :

1 mg

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, neutralization, blocking or activating experiments

more info or order :

R&D Systems product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; mouse; 0.4 ug/ml; fig 7	Liu C, Rajapakse A, Riedo E, Fellay B, Bernhard M, Montani J, et al. Targeting arginase-II protects mice from high-fat-diet-induced hepatic steatosis through suppression of macrophage inflammation. Sci Rep. 2016;6:20405 pubmed publisher
	Sakai M, Yu Z, Taniguchi M, Picotin R, Oyama N, Stellwagen D, et al. N-Acetylcysteine Suppresses Microglial Inflammation and Induces Mortality Dose-Dependently via Tumor Necrosis Factor-α Signaling. Int J Mol Sci. 2023;24: pubmed publisher
	Liu X, Zu E, Chang X, Ma X, Wang Z, Song X, et al. Bi-phasic effect of gelatin in myogenesis and skeletal muscle regeneration. Dis Model Mech. 2021;14: pubmed publisher
	Sato K, Tobo A, Mogi C, Tobo M, Yamane N, Tosaka M, et al. The protective role of proton-sensing TDAG8 in the brain injury in a mouse ischemia reperfusion model. Sci Rep. 2020;10:17193 pubmed publisher
	Xu C, Wang L, Zhang Y, Li W, Li J, Wang Y, et al. Tubule-Specific Mst1/2 Deficiency Induces CKD via YAP and Non-YAP Mechanisms. J Am Soc Nephrol. 2020;31:946-961 pubmed publisher
	Ono Y, Maejima Y, Saito M, Sakamoto K, Horita S, Shimomura K, et al. TAK-242, a specific inhibitor of Toll-like receptor 4 signalling, prevents endotoxemia-induced skeletal muscle wasting in mice. Sci Rep. 2020;10:694 pubmed publisher
	Mahmoudi S, Mancini E, Xu L, Moore A, Jahanbani F, Hebestreit K, et al. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing. Nature. 2019;574:553-558 pubmed publisher
	Myles I, Anderson E, Earland N, Zarember K, Sastalla I, Williams K, et al. TNF overproduction impairs epithelial staphylococcal response in hyper IgE syndrome. J Clin Invest. 2018;128:3595-3604 pubmed publisher
	Ono Y, Sakamoto K. Lipopolysaccharide inhibits myogenic differentiation of C2C12 myoblasts through the Toll-like receptor 4-nuclear factor-?B signaling pathway and myoblast-derived tumor necrosis factor-?. PLoS ONE. 2017;12:e0182040 pubmed publisher

product information

master code :

AB-410-NA

SKU :

AB-410-NA

product name :

Mouse TNF-alpha Antibody

unit size :

1 mg

description :

The Mouse TNF-alpha Antibody from R&D Systems is a goat polyclonal antibody to TNF-alpha. This antibody reacts with mouse,rat,transgenic mouse. The Mouse TNF-alpha Antibody has been validated for the following applications: Neutralization,In vivo assay,Western Blot,Cell Culture,Immunohistochemistry.

target :

TNF-alpha

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant mouse TNF-alpha , Leu80-Leu235, Accession # P06804

isotype :

IgG

purity :

Protein A or G purified

species :

Mouse,Rat,Transgenic Mouse

specificity :

Detects mouse TNF-alpha in direct ELISAs and Western blots. In direct ELISAs, approximately 15% cross-reactivity with human TNF-alpha is observed, and less than 5% cross-reactivity with recombinant bovine TNF-alpha , recombinant canine TNF-alpha , recombinant equine TNF-alpha , recombinant feline TNF-alpha , and recombinant porcine TNF-alpha is observed.

gene symbol :

TNF

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cytotoxicity Induced by TNF-a and Neutralization by Mouse TNF-a Antibody.

accessionNumbers :

P06804

applications :

Neutralization,In vivo assay,Western Blot,Cell Culture,Immunohistochemistry

USD :

509 USD

alt names :

APC1 protein, Cachectin, Cachetin, DIF, TNF, TNF, monocyte-derived, TNF-a, TNFA, TNFalpha, TNF-alphacachectin, TNFATNF, macrophage-derived, TNFG1F, TNFSF1A, TNFSF2, TNFSF2TNF superfamily, member 2, tumor necrosis factor, tumor necrosis factor (TNF superfamily, member 2), tumor necrosis factor alpha, Tumor necrosis factor ligand superfamily member 2, tumor necrosis factor-alpha

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage