Human IL-12 Antibody | R&D Systems AB-219-NA product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-12 Antibody

catalog :

AB-219-NA

quantity :

1 mg

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, neutralization

more info or order :

R&D Systems product webpage

citations: 3

Reference
Nirschl C, Brodkin H, Domonkos C, Dwyer C, Hicklin D, Ismail N, et al. mWTX-330, an IL-12 INDUKINE Molecule, Activates and Reshapes Tumor-Infiltrating CD8+ T and NK Cells to Generate Antitumor Immunity. Cancer Immunol Res. 2023;11:962-977 pubmed publisher
Kong W, Biswas A, Zhou D, Fiches G, Fujinaga K, Santoso N, et al. Nucleolar protein NOP2/NSUN1 suppresses HIV-1 transcription and promotes viral latency by competing with Tat for TAR binding and methylation. PLoS Pathog. 2020;16:e1008430 pubmed publisher
Huang H, Liu S, Jean M, Simpson S, Huang H, Merkley M, et al. A Novel Bromodomain Inhibitor Reverses HIV-1 Latency through Specific Binding with BRD4 to Promote Tat and P-TEFb Association. Front Microbiol. 2017;8:1035 pubmed publisher

product information

master code :

AB-219-NA

SKU :

AB-219-NA

product name :

Human IL-12 Antibody

unit size :

1 mg

description :

The Human IL-12 Antibody from R&D Systems is a goat polyclonal antibody to IL-12. This antibody reacts with human. The Human IL-12 Antibody has been validated for the following applications: Bioassay,Western Blot,Neutralization,Cell Culture.

target :

IL-12

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-12 heterodimer, Arg23-Ser219 of p35; Ile23-Ser328 of p40, Accession # P29459 (p35) & P29460 (p40)

isotype :

IgG

purity :

Protein A or G purified

species :

Human

specificity :

Detects human IL-12 in direct ELISAs and Western blots. In these formats, less than 2% cross-reactivity with recombinant mouse IL-12 is observed.

gene symbol :

IL12A

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced by IL-12 and Neutralization by Human IL-12 Antibody.

accessionNumbers :

P29459 (p35) P29460 (p40)

applications :

Western Blot,Neutralization,Cell Culture

USD :

509 USD

alt names :

CLMF p35, CLMF1, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL12, IL-12 subunit p35, IL-12, subunit p35, IL12A, interleukin 12, p35, interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocytematuration factor 1, p35), interleukin-12 alpha chain, interleukin-12 subunit alpha, natural killer cell stimulatory factor 1, 35 kD subunit, NF cell stimulatory factor chain 1, NK cell stimulatory factor chain 1, NKSF1, p35

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage