product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human IL-8/CXCL8 Antibody
catalog :
AB-208-NA
quantity :
1 mg
price :
509 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunocytochemistry, neutralization
more info or order :
citations: 5
Reference
Patankar M, Li M, Khalatbari A, Castle J, Hu L, Zhang C, et al. Inflammatory and Proliferative Pathway Activation in Human Esophageal Myofibroblasts Treated with Acidic Bile Salts. Int J Mol Sci. 2022;23: pubmed publisher
Sheshadri N, Poria D, Sharan S, Hu Y, Yan C, Koparde V, et al. PERK signaling through C/EBPδ contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells. Cell Death Dis. 2021;12:1038 pubmed publisher
Angelini A, Miyabe Y, Newsted D, Kwan B, Miyabe C, Kelly R, et al. Directed evolution of broadly crossreactive chemokine-blocking antibodies efficacious in arthritis. Nat Commun. 2018;9:1461 pubmed publisher
Lin Z, Zhang Y, Xia Y, Xu X, Jiao X, Sun J. Salmonella enteritidis Effector AvrA Stabilizes Intestinal Tight Junctions via the JNK Pathway. J Biol Chem. 2016;291:26837-26849 pubmed publisher
Williams A, José R, Mercer P, Brealey D, Parekh D, Thickett D, et al. Evidence for chemokine synergy during neutrophil migration in ARDS. Thorax. 2017;72:66-73 pubmed publisher
product information
brand :
R&D Systems
master code :
AB-208-NA
SKU :
AB-208-NA
product name :
Human IL-8/CXCL8 Antibody
unit size :
1 mg
seo description :
The Human IL-8/CXCL8 Antibody from R&D Systems is a goat polyclonal antibody to CXCL8/IL-8. This antibody reacts with human. The Human IL-8/CXCL8 Antibody has been validated for the following applications: ELISA Development (Capture),Control,Neutralization,Functional Assay,Immunocytochemistry,Western Blot.
target :
IL-8/CXCL8
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Neutralization 5-20 ug/mL
host :
Goat
immunogen :
E. coli-derived recombinant human IL-8/CXCL8, Ser28-Ser99, Accession # P10145
isotype :
IgG
purity :
Protein A or G purified
species :
Human
specificity :
Detects human IL-8/CXCL8 in direct ELISAs and Western blots. In direct ELISAs, approximately 15% cross-reactivity with recombinant human (rh) GRO alpha , rhGRO▀, and rhGRO gamma is observed, and less than 1% cross-reactivity with recombinant feline IL-8/CXCL8, recombinant porcine IL-8/CXCL8, and recombinant canine IL-8/CXCL8 is observed.
gene symbol :
IL8
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Chemotaxis Induced by IL-8/CXCL8 and Neutralization by Human IL-8/CXCL8 Antibody.
accessionNumbers :
P10145
applications :
Western Blot,ELISA Development (Capture),Control,Neutralization,Immunocytochemistry,Functional Assay
USD :
509 USD
alt names :
3-10C, AMCF-I, C-X-C motif chemokine 8, CXCL8, CXCL8SCYB8, Emoctakin, GCP1, GCP-1TSG-1, IL8, interleukin 8, K60, LAI, LECT, LUCT, LYNAP, MDNCF, MDNCFb-ENAP, member 8, MONAP, MONAPGCP1, NAF, NAP1, NAP-1NAP1, NCF, Neutrophil-activating protein 1, Protein 3-10C, T cell chemotactic factor, T-cell chemotactic factor, TCF, TSG1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.