product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human IL-6 Antibody
catalog :
AB-206-NA
quantity :
1 mg
price :
529 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, neutralization
more info or order :
citations: 5
Reference
Zhu H, Chan K, Huang X, Cerra C, Blake S, Trigos A, et al. Cystathionine-β-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation. elife. 2022;11: pubmed publisher
Tyler E, Gutierrez Del Arroyo A, Hughes B, Wallis R, Garbe J, Stampfer M, et al. Early growth response 2 (EGR2) is a novel regulator of the senescence programme. Aging Cell. 2021;20:e13318 pubmed publisher
Findeisen M, Allen T, Henstridge D, Kammoun H, Brandon A, Baggio L, et al. Treatment of type 2 diabetes with the designer cytokine IC7Fc. Nature. 2019;574:63-68 pubmed publisher
Borghesan M, Fafián Labora J, Eleftheriadou O, Carpintero Fernández P, Pàez Ribes M, Vizcay Barrena G, et al. Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3. Cell Rep. 2019;27:3956-3971.e6 pubmed publisher
McLean K, Tan L, Bolland D, Coffman L, Peterson L, Talpaz M, et al. Leukemia inhibitory factor functions in parallel with interleukin-6 to promote ovarian cancer growth. Oncogene. 2019;38:1576-1584 pubmed publisher
product information
master code :
AB-206-NA
SKU :
AB-206-NA
product name :
Human IL-6 Antibody
unit size :
1 mg
description :
The Human IL-6 Antibody from R&D Systems is a goat polyclonal antibody to IL-6. This antibody reacts with human,mouse. The Human IL-6 Antibody has been validated for the following applications: Neutralization,Western Blot,ELISA Capture,Simple Western.
target :
IL-6
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant human IL-6, Pro29-Met212, Accession # P05231
isotype :
IgG
purity :
Protein A or G purified
species :
Human,Mouse
specificity :
Detects human IL-6 in direct ELISAs and Western blots. In these formats, less than 5% cross-reactivity with recombinant mouse IL-6, recombinant bovine IL-6, recombinant porcine IL-6, recombinant equine IL-6, recombinant feline IL-6, recombinant rat IL-6, recombinant cotton rat IL-6, recombinant rabbit IL-6, and recombinant viral IL-6 is observed.
gene symbol :
IL6
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Cell Proliferation Induced by IL-6 and Neutralization by Human IL-6 Antibody.
accessionNumbers :
P05231
applications :
Neutralization,Western Blot,ELISA Capture,Simple Western
USD :
529 USD
alt names :
B-cell differentiation factor, B-cell stimulatory factor 2, BSF2, BSF-2, CDF, CTL differentiation factor, HSF, hybridoma growth factor, IFNB2, IFN-beta-2, IL6, IL-6, Interferon beta-2, interleukin 6 (interferon, beta 2), interleukin BSF-2, interleukin-6, MGI-2A
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.