TGF┐▀ Pan Specific Antibody | R&D Systems AB-100-NA product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

TGF┐▀ Pan Specific Antibody

catalog :

AB-100-NA

quantity :

1 mg

price :

549 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section, blocking or activating experiments

more info or order :

R&D Systems product webpage

citations: 33

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:500	Lund A, Wagner M, Fankhauser M, Steinskog E, Broggi M, Spranger S, et al. Lymphatic vessels regulate immune microenvironments in human and murine melanoma. J Clin Invest. 2016;126:3389-402 pubmed publisher
blocking or activating experiments; mouse; fig s4	Wang S, Gao X, Shen G, Wang W, Li J, Zhao J, et al. Interleukin-10 deficiency impairs regulatory T cell-derived neuropilin-1 functions and promotes Th1 and Th17 immunity. Sci Rep. 2016;6:24249 pubmed publisher
	Liu Y, Teng A. Potential contribution of immature myeloid CD11c+dendritic cells-derived osteoclast precursor to inflammation-induced bone loss in the TRAF6-null chimeras in-vivo. J Dent Sci. 2023;18:1372-1377 pubmed publisher
	Kamal N, Hamouda M, Abdelgawad N. Expression of TGF-β and MMP-2 in hereditary gingival fibromatosis epithelial cells. A possible contribution of the epithelium to its pathogenesis. J Oral Biol Craniofac Res. 2022;12:617-622 pubmed publisher
	Gokavi J, Sadawarte S, Shelke A, Kulkarni Kale U, Thakar M, Saxena V. Inhibition of miR-155 Promotes TGF-β Mediated Suppression of HIV Release in the Cervical Epithelial Cells. Viruses. 2021;13: pubmed publisher
	Shi A, Li J, Qiu X, Sabbah M, Boroumand S, Huang T, et al. TGF-β loaded exosome enhances ischemic wound healing in vitro and in vivo. Theranostics. 2021;11:6616-6631 pubmed publisher
	Panahipour L, Husejnovic S, Nasirzade J, Semelmayer S, Gruber R. Micellar Casein and Whey Powder Hold a TGF-β Activity and Regulate ID Genes In Vitro. Molecules. 2021;26: pubmed publisher
	Choi Y, Song M, Hara M, Imanaka Yoshida K, Lee D, Chung J, et al. Effects of Tenascin C on the Integrity of Extracellular Matrix and Skin Aging. Int J Mol Sci. 2020;21: pubmed publisher
	Panahipour L, Kargarpour Z, Laggner M, Mildner M, Ankersmit H, Gruber R. TGF-β in the Secretome of Irradiated Peripheral Blood Mononuclear Cells Supports In Vitro Osteoclastogenesis. Int J Mol Sci. 2020;21: pubmed publisher
	Jankowska Gan E, Agashe V, Lema D, Zhou Y, Gonzalez Bosc L, Sullivan J, et al. Donor HLA-DR Drives the Development of De Novo Autoimmunity Following Lung and Heart Transplantation. Transplant Direct. 2020;6:e607 pubmed publisher
	Lei M, Wang K, Li S, Zhao K, Hua W, Wu X, et al. The c-Jun signaling pathway has a protective effect on nucleus pulposus cells in patients with intervertebral disc degeneration. Exp Ther Med. 2020;20:123 pubmed publisher
	Panahipour L, Kargarpour Z, Luza B, Lee J, Gruber R. TGF-β Activity Related to the Use of Collagen Membranes: In Vitro Bioassays. Int J Mol Sci. 2020;21: pubmed publisher
	Ji L, Wang T, Tian L, Song H, Gao M. Roxatidine inhibits fibrosis by inhibiting NF‑κB and MAPK signaling in macrophages sensing breast implant surface materials. Mol Med Rep. 2020;21:161-172 pubmed publisher
	Devocelle A, Lecru L, Francois H, Desterke C, Gallerne C, Eid P, et al. Inhibition of TGF-β1 Signaling by IL-15: A Novel Role for IL-15 in the Control of Renal Epithelial-Mesenchymal Transition: IL-15 Counteracts TGF-β1-Induced EMT in Renal Fibrosis. Int J Cell Biol. 2019;2019:9151394 pubmed publisher
	Martinez Useros J, Garcia Carbonero N, Li W, Fernández Aceñero M, Cristobal I, Rincón R, et al. UNR/CSDE1 Expression Is Critical to Maintain Invasive Phenotype of Colorectal Cancer through Regulation of c-MYC and Epithelial-to-Mesenchymal Transition. J Clin Med. 2019;8: pubmed publisher
	Abdulreda M, Berman D, Shishido A, Martin C, Hossameldin M, Tschiggfrie A, et al. Operational immune tolerance towards transplanted allogeneic pancreatic islets in mice and a non-human primate. Diabetologia. 2019;62:811-821 pubmed publisher
	García Rocha R, Monroy García A, Hernández Montes J, Weiss Steider B, Gutiérrez Serrano V, Del Carmen Fuentes Castañeda M, et al. Cervical cancer cells produce TGF-β1 through the CD73-adenosine pathway and maintain CD73 expression through the autocrine activity of TGF-β1. Cytokine. 2018;: pubmed publisher
	Zheng J, Mei Y, Xiang P, Zhai G, Zhao N, Xu C, et al. DNA methylation affects metastasis of renal cancer and is associated with TGF-β/RUNX3 inhibition. Cancer Cell Int. 2018;18:56 pubmed publisher
	Hulsmans M, Sager H, Roh J, Valero Muñoz M, Houstis N, Iwamoto Y, et al. Cardiac macrophages promote diastolic dysfunction. J Exp Med. 2018;215:423-440 pubmed publisher
	Xiao J, Yu K, Li M, Xiong C, Wei Y, Zeng Q. The IL-2/Anti-IL-2 Complex Attenuates Cardiac Ischaemia-Reperfusion Injury Through Expansion of Regulatory T Cells. Cell Physiol Biochem. 2017;44:1810-1827 pubmed publisher
	Ibrahim M, Scozzi D, Toth K, Ponti D, Kreisel D, Menna C, et al. Naive CD4+ T Cells Carrying a TLR2 Agonist Overcome TGF-β-Mediated Tumor Immune Evasion. J Immunol. 2018;200:847-856 pubmed publisher
	Olsen O, Skjærvik A, Størdal B, Sundan A, Holien T. TGF-? contamination of purified recombinant GDF15. PLoS ONE. 2017;12:e0187349 pubmed publisher
	Rouf R, MacFarlane E, Takimoto E, Chaudhary R, Nagpal V, Rainer P, et al. Nonmyocyte ERK1/2 signaling contributes to load-induced cardiomyopathy in Marfan mice. JCI Insight. 2017;2: pubmed publisher
	Selvamurugan N, He Z, Rifkin D, Dabovic B, Partridge N. Pulsed Electromagnetic Field Regulates MicroRNA 21 Expression to Activate TGF-β Signaling in Human Bone Marrow Stromal Cells to Enhance Osteoblast Differentiation. Stem Cells Int. 2017;2017:2450327 pubmed publisher
	Yang Y, Liu H, Zhang H, Ye Q, Wang J, Yang B, et al. ST2/IL-33-Dependent Microglial Response Limits Acute Ischemic Brain Injury. J Neurosci. 2017;37:4692-4704 pubmed publisher
	Pozzer D, Favellato M, Bolis M, Invernizzi R, Solagna F, Blaauw B, et al. Endoplasmic Reticulum Oxidative Stress Triggers Tgf-Beta-Dependent Muscle Dysfunction by Accelerating Ascorbic Acid Turnover. Sci Rep. 2017;7:40993 pubmed publisher
	Poveda J, Sanz A, Fernández Fernández B, Carrasco S, Ruiz Ortega M, Cannata Ortiz P, et al. MXRA5 is a TGF-?1-regulated human protein with anti-inflammatory and anti-fibrotic properties. J Cell Mol Med. 2017;21:154-164 pubmed publisher
	Chen X, Rateri D, Howatt D, Balakrishnan A, Moorleghen J, Cassis L, et al. TGF-β Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions. PLoS ONE. 2016;11:e0153811 pubmed publisher
	Veltmann M, Hollborn M, Reichenbach A, Wiedemann P, Kohen L, Bringmann A. Osmotic Induction of Angiogenic Growth Factor Expression in Human Retinal Pigment Epithelial Cells. PLoS ONE. 2016;11:e0147312 pubmed publisher
	Angelucci C, Maulucci G, Colabianchi A, Iacopino F, D Alessio A, Maiorana A, et al. Stearoyl-CoA desaturase 1 and paracrine diffusible signals have a major role in the promotion of breast cancer cell migration induced by cancer-associated fibroblasts. Br J Cancer. 2015;112:1675-86 pubmed publisher
	Zhang P, Lo A, Huang Y, Huang G, Liang G, Mott J, et al. Identification of genetic loci that control mammary tumor susceptibility through the host microenvironment. Sci Rep. 2015;5:8919 pubmed publisher
	Hou X, Song J, Su J, Huang D, Gao W, Yan J, et al. CD4(+)Foxp3(+) Tregs protect against innate immune cell-mediated fulminant hepatitis in mice. Mol Immunol. 2015;63:420-7 pubmed publisher
	Koli K, Wempe F, Sterner Kock A, Kantola A, Komor M, Hofmann W, et al. Disruption of LTBP-4 function reduces TGF-beta activation and enhances BMP-4 signaling in the lung. J Cell Biol. 2004;167:123-33 pubmed

product information

master code :

AB-100-NA

SKU :

AB-100-NA

product name :

TGF┐▀ Pan Specific Antibody

unit size :

1 mg

description :

The TGF¿ß Pan Specific Antibody from R&D Systems is a rabbit polyclonal antibody to TGF-beta. This antibody reacts with bovine,goat,human,mink,mouse,multi-species,primate - macaca mulatta (rhesus macaque),primate - papio hamadryas (hamadryas baboon),rat,transgenic mouse. The TGF¿ß Pan Specific Antibody has been validated for the following applications: Neutralization,Immunohistochemistry,Bioassay,Blocking,Western Blot,Electron Microscopy,Cell Culture,Immunohistochemistry-Paraffin,In vivo assay,Immunocytochemistry.

target :

TGF-beta

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Recombinant human TGF┐▀1, porcine platelet-derived TGF┐▀1.2, porcine platelet-derived TGF┐▀2, and recombinant amphibian TGF┐▀5

isotype :

IgG

purity :

Protein A or G purified

species :

Bovine,Goat,Human,Mink,Mouse,Multi-Species,Primate - Macaca mulatta (Rhesus Macaque),Rat,Transgenic Mouse

specificity :

Detects TGF┐▀1, TGF┐▀1.2, TGF┐▀2, TGF┐▀3, and TGF┐▀5 in direct ELISAs and Western blots.

gene symbol :

TGFB1

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

TGF-beta Pan Specific antibody in Human Prostate Tissue by Immunohistochemistry (IHC-P).

applications :

Neutralization,Bioassay,Blocking,Western Blot,Electron Microscopy,Cell Culture,Immunohistochemistry,Immunohistochemistry-Paraffin,In vivo assay,Immunocytochemistry

USD :

549 USD

alt names :

ARVD1, CED, DPD1, LAP, LDS5, RNHF, TGF beta1, TGFB, TGFB1, TGFb1.2, TGFB2, TGFB3, TGFbeta, TGFbeta 1, TGFbeta 1.2, TGFbeta 2, TGFbeta 3, TGFbeta 5, transforming growth factor beta 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage