product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IL-39 Fc Chimera Protein, CF
catalog :
9990-IL-050
quantity :
50 ug
price :
573 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Xiao H, Alisic H, Reiman B, Deng Z, Zhu Z, Givens N, et al. IL-39 Reduces Proliferation and Promotes Apoptosis of Bladder Cancer by Altering the Activity of Cyclin E and Fas. Anticancer Res. 2021;41:2239-2245 pubmed publisher
Cassatella M, Gardiman E, Arruda Silva F, Bianchetto Aguilera F, Gasperini S, Bugatti M, et al. Human neutrophils activated by TLR8 agonists, with or without IFNγ, synthesize and release EBI3, but not IL-12, IL-27, IL-35, or IL-39. J Leukoc Biol. 2020;108:1515-1526 pubmed publisher
product information
master code :
9990-IL
SKU :
9990-IL-050
product name :
Recombinant Human IL-39 Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Human IL-39 Fc Chimera Protein, CF from R&D Systems is derived from HEK293. The Recombinant Human IL-39 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
IL-39 (IL-23p19/EBI3)
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
70-77 kDa, reducing conditions
theoretical molecular weight :
69 kDa
details of functionality :
Measured by its ability to induce IFN-gamma production by mouse splenocytes. The ED50 for this effect is 50-250 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Human IL-39 Fc Chimera Protein Bioactivity
accessionNumbers :
Q14213, Q9NPF7
applications :
Bioactivity
source long :
Human embryonic kidney cell, HEK293-derived human IL-39 (IL-23p19/EBI3) protein Human EBI3 (Arg21-Lys229, Gln95Cys) Accession # Q14213 GGGSGGGSGGGS Human IL-23p19 (Arg20-Pro189) Accession # Q9NPF7 IEGRMD Human IgG1 (Pro100-Lys330)
source short :
HEK293
USD :
573 USD
storage :
12 months from date of receipt, <= -20 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, <= -20 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.