Recombinant Mouse Angiopoietin-1 Protein | R&D Systems 9936-AN-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Angiopoietin-1 Protein

catalog :

9936-AN-025

quantity :

25 ug

price :

503 USD

citations: 3

Reference
Liu F, Cho Y, Fridayana F, Niloofar L, Vo M, Huang Y, et al. MT-100, a human Tie2-agonistic antibody, improves penile neurovasculature in diabetic mice via the novel target Srpx2. Exp Mol Med. 2025;57:104-117 pubmed publisher
Luck R, Karakatsani A, Shah B, Schermann G, Adler H, Kupke J, et al. The angiopoietin-Tie2 pathway regulates Purkinje cell dendritic morphogenesis in a cell-autonomous manner. Cell Rep. 2021;36:109522 pubmed publisher
Sala Jarque J, Mesquida Veny F, Badiola Mateos M, Samitier J, Hervera A, del Río J. Neuromuscular Activity Induces Paracrine Signaling and Triggers Axonal Regrowth after Injury in Microfluidic Lab-On-Chip Devices. Cells. 2020;9: pubmed publisher

product information

master code :

9936-AN

SKU :

9936-AN-025

product name :

Recombinant Mouse Angiopoietin-1 Protein

unit size :

25 ug

description :

The Recombinant Mouse Angiopoietin-1 Protein from R&D Systems is derived from NS0. The Recombinant Mouse Angiopoietin-1 Protein has been validated for the following applications: Bioactivity.

target :

Angiopoietin-1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris-Citrate and NaCl with Trehalose and with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Mouse

observed molecular weight :

59-75 kDa, reducing conditions

theoretical molecular weight :

56 kDa

details of functionality :

Measured by its ability to inhibit serum deprivation induced apoptosis in HUVEC human umbilical vein endothelial cells. Kwak,áH.J. etáal . (1999) FEBS Letters 448 :249. The ED50 for this effect is 10-50 ng/mL in the presence of 5 ╡g/mL of a cross-linking antibody, Mouse Anti-polyHistidine Monoclonal Antibody (Catalog # MAB050 ).

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Mouse Angiopoietin-1 Protein Bioactivity

accessionNumbers :

O08538

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse Angiopoietin-1 protein Mouse Angiopoietin-1 (Ser20-Leu261) Accession # O08538 GGGSGGGSGGGS Mouse Angiopoietin-1 (Arg277-Phe498) Accession # O08538 HHHHHH N-terminus C-terminus

source short :

NS0

USD :

503 USD

alt names :

AGP1, AGPT, Ang1, ANG-1, angiopoietin 1, angiopoietin-1, ANGPT1, KIAA0003

storage :

12 months from date of receipt, <= -20 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, <= -20 ░C under sterile conditions after reconstitution.