Recombinant Human S100A8 Protein, CF | R&D Systems 9876-S8-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human S100A8 Protein, CF

catalog :

9876-S8-050

quantity :

50 ug

price :

432 USD

citations: 4

Reference
Chen Q, Ishii K, Mori H, Nishijima A, Arai S, Miyazaki T, et al. Cryo-EM reveals structural basis for human AIM/CD5L recognition of polymeric immunoglobulin M. Nat Commun. 2024;15:9387 pubmed publisher
Henrioux F, Navel V, Belville C, Charnay C, Antoine A, Chiambaretta F, et al. Inflammation of Dry Eye Syndrome: A Cellular Study of the Epithelial and Macrophagic Involvement of NFAT5 and RAGE. Int J Mol Sci. 2023;24: pubmed publisher
Drosatos I, Tsoporis J, Izhar S, Gupta S, Tsirebolos G, Sakadakis E, et al. Differential Regulation of Circulating Soluble Receptor for Advanced Glycation End Products (sRAGEs) and Its Ligands S100A8/A9 Four Weeks Post an Exercise Intervention in a Cohort of Young Army Recruits. Biomolecules. 2021;11: pubmed publisher
Maehara N, Taniguchi K, Okuno A, Ando H, Hirota A, Li Z, et al. AIM/CD5L attenuates DAMPs in the injured brain and thereby ameliorates ischemic stroke. Cell Rep. 2021;36:109693 pubmed publisher

product information

master code :

9876-S8

SKU :

9876-S8-050

product name :

Recombinant Human S100A8 Protein, CF

unit size :

50 ug

description :

The Recombinant Human S100A8 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human S100A8 Protein, CF has been validated for the following applications: Bioactivity.

target :

S100A8

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris and TCEP with Trehalose.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

9 kDa, reducing conditions

theoretical molecular weight :

11 kDa

details of functionality :

Measured by its ability to induce CXCL1/KC secretion by C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is 20 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Human S100A8 Protein Bioactivity

accessionNumbers :

P05109

applications :

Bioactivity

source long :

E. coli -derived human S100A8 protein Met1-Glu93

source short :

E. coli

USD :

432 USD

alt names :

60B8AG, CAGACP-10, calgranulin A, Calgranulin-A, Calprotectin L1L subunit, CFAG, CFAGL1Ag, CGLA, Cystic fibrosis antigen, Leukocyte L1 complex light chain, MA387, MIF, Migration inhibitory factor-related protein 8, MRP8, MRP-8, MRP8S100 calcium binding protein A8 (calgranulin A), NIF, P8, protein S100-A8, S100 calcium binding protein A8, S100 calcium-binding protein A8, S100 calcium-binding protein A8 (calgranulin A), Urinary stone protein band A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, <= -20 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, <= -20 ░C under sterile conditions after reconstitution.