Recombinant Mouse Neuregulin-1/NRG1 Protein, CF | R&D Systems 9875-NR-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Neuregulin-1/NRG1 Protein, CF

catalog :

9875-NR-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 11

Reference
Bergersen K, Kavvathas B, Ford B, Wilson E. Toxoplasma infection induces an aged neutrophil population in the CNS that is associated with neuronal protection. J Neuroinflammation. 2024;21:189 pubmed publisher
Hoving J, Harford Wright E, Wingfield Digby P, Cattin A, Campana M, Power A, et al. N-cadherin directs the collective Schwann cell migration required for nerve regeneration through Slit2/3-mediated contact inhibition of locomotion. elife. 2024;13: pubmed publisher
Chougoni K, Park H, Damle P, Mason T, Cheng B, Dcona M, et al. Coordinate transcriptional regulation of ErbB2/3 by C-terminal binding protein 2 signals sensitivity to ErbB2 inhibition in pancreatic adenocarcinoma. Oncogenesis. 2023;12:53 pubmed publisher
Patel S, Sparman N, Arneson D, Alvarsson A, Santos L, Duesman S, et al. Mammary duct luminal epithelium controls adipocyte thermogenic programme. Nature. 2023;620:192-199 pubmed publisher
Andries L, Kancheva D, Masin L, Scheyltjens I, Van Hove H, De Vlaminck K, et al. Immune stimulation recruits a subset of pro-regenerative macrophages to the retina that promotes axonal regrowth of injured neurons. Acta Neuropathol Commun. 2023;11:85 pubmed publisher
Chiasson MacKenzie C, Vitte J, Liu C, Wright E, Flynn E, Stott S, et al. Cellular mechanisms of heterogeneity in NF2-mutant schwannoma. Nat Commun. 2023;14:1559 pubmed publisher
Banerjee S, Mishra S, Xu W, Thompson W, Chowdhury I. Neuregulin-1 signaling regulates cytokines and chemokines expression and secretion in granulosa cell. J Ovarian Res. 2022;15:86 pubmed publisher
Westendorp F, Karpus O, Koelink P, Vermeulen J, Meisner S, Koster J, et al. Epithelium-derived Indian Hedgehog restricts stromal expression of ErbB family members that drive colonic tumor cell proliferation. Oncogene. 2021;40:1628-1643 pubmed publisher
Huang T, Wu H, Chen S, Wang Y, Wu C. Thrombomodulin facilitates peripheral nerve regeneration through regulating M1/M2 switching. J Neuroinflammation. 2020;17:240 pubmed publisher
Gomis Coloma C, Velasco Aviles S, Gomez Sanchez J, Casillas Bajo A, Backs J, Cabedo H. Class IIa histone deacetylases link cAMP signaling to the myelin transcriptional program of Schwann cells. J Cell Biol. 2018;217:1249-1268 pubmed publisher
Cornelison R, Gonzalez Rothi E, Porvasnik S, Wellman S, Park J, Fuller D, et al. Injectable hydrogels of optimized acellular nerve for injection in the injured spinal cord. Biomed Mater. 2018;13:034110 pubmed publisher

product information

brand :

R&D Systems

master code :

9875-NR

SKU :

9875-NR-050

product name :

Recombinant Mouse Neuregulin-1/NRG1 Protein, CF

unit size :

50 ug

seo description :

The Recombinant Mouse Neuregulin-1/NRG1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Neuregulin-1/NRG1 Protein, CF has been validated for the following applications: Bioactivity.

target :

Neuregulin-1/NRG1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Mouse

observed molecular weight :

42-49 kDa, reducing conditions

theoretical molecular weight :

26 kDa

details of functionality :

Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. Karey, K.P. et al . (1988) Cancer Research 48 :4083. The ED50 for this effect is 0.9-5.4 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Mouse Neuregulin-1/NRG1 Protein Bioactivity

accessionNumbers :

XP_006509143

applications :

Bioactivity

source :

NS0-derived Recombinant Mouse Neuregulin-1/NRG1 Protein, CF

USD :

432 USD

alt names :

ARIA, GGF2, GGFglial growth factor, Heregulin-1, HGL, HGLneu differentiation factor, HRG, HRG1, HRG1-alpha, HRG1-beta 1, HRGAneuregulin 1 type IV beta 1a, MST131, MSTP131, NDFheregulin, alpha (45kD, ERBB2 p185-activator), neuregulin 1, neuregulin 1 type IV beta 3, Neuregulin1, NRG1, pro-neuregulin-1, membrane-bound isoform, pro-NRG1, sensory and motor neuron derived factor, SMDF

storage :

12 months from date of receipt, <= -20 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, <= -20 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage