product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Gas6 Protein
catalog :
986-GS-025
quantity :
25 ug
price :
509 USD
more info or order :
citations: 24
Reference |
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Lee Y, Park H, Woo S, Park E, Kang J. RhoA/phosphatidylinositol 3-kinase/protein kinase B/mitogen-activated protein kinase signaling after growth arrest-specific protein 6/mer receptor tyrosine kinase engagement promotes epithelial cell growth and wound repair via upregulation of hepatoc. J Pharmacol Exp Ther. 2014;350:563-77 pubmed publisher
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Uehara H, Shacter E. Auto-oxidation and oligomerization of protein S on the apoptotic cell surface is required for Mer tyrosine kinase-mediated phagocytosis of apoptotic cells. J Immunol. 2008;180:2522-30 pubmed
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Rothlin C, Ghosh S, Zuniga E, Oldstone M, Lemke G. TAM receptors are pleiotropic inhibitors of the innate immune response. Cell. 2007;131:1124-36 pubmed
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Sather S, Kenyon K, Lefkowitz J, Liang X, Varnum B, Henson P, et al. A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation. Blood. 2007;109:1026-33 pubmed
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product information
brand :
R&D Systems
master code :
986-GS
SKU :
986-GS-025
product name :
Recombinant Mouse Gas6 Protein
unit size :
25 ug
seo description :
The Recombinant Mouse Gas6 Protein from R&D Systems is derived from NS0. The Recombinant Mouse Gas6 Protein has been validated for the following applications: Binding Activity.
target :
Gas6
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
dilution :
Binding Activity
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Mouse
observed molecular weight :
72 kDa, reducing conditions
theoretical molecular weight :
62 kDa
gene symbol :
Gas6
details of functionality :
Measured by its ability to down regulate the expression of Axl in DU145 human prostate carcinoma cells. Mishra, A. etáal . (2012) Mol. Cancer Res. 10 :703. The ED50 for this effect is 20-100 ng/mL.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
CAA42507
applications :
Binding Activity
source :
NS0-derived Recombinant Mouse Gas6 Protein
USD :
509 USD
alt names :
AXLLG, AXLLGAXL stimulatory factor, AXSFAXL receptor tyrosine kinase ligand, DKFZp666G247, FLJ34709, GAS-6, growth arrest-specific 6, growth arrest-specific protein 6
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information

R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
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