product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse IL-3R alpha/CD123 Fc Chimera Protein, CF
catalog :
983-MR-100
quantity :
100 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Mille F, Llambi F, Guix C, Delloye Bourgeois C, Guenebeaud C, Castro Obregon S, et al. Interfering with multimerization of netrin-1 receptors triggers tumor cell death. Cell Death Differ. 2009;16:1344-51 pubmed publisher
product information
master code :
983-MR
SKU :
983-MR-100
product name :
Recombinant Mouse IL-3R alpha/CD123 Fc Chimera Protein, CF
unit size :
100 ug
description :
The Recombinant Mouse IL-3R alpha/CD123 Fc Chimera Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Mouse IL-3R alpha/CD123 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
IL-3R alpha
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
70-80 kDa, reducing conditions
theoretical molecular weight :
61.0 kDa (monomer)
gene symbol :
Il3ra
details of functionality :
Measured by its ability to inhibit the IL-3-induced proliferation of NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 0.03-0.15 ╡g/mL in the presence of 2.5 ╡g/mL Recombinant Mouse IL-3 R▀ Fc Chimera (Catalog # 549-R3 ) and 2 ng/mL of Recombinant Mouse IL-3 (Catalog # 403-ML ).
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P26952
applications :
Bioactivity
source long :
Spodoptera frugiperda , Sf 21 (baculovirus)-derived mouse IL-3 R alpha/CD123 protein Mouse IL-3 R alpha (Ser17-Lys331) Accession # P26952 IEGRID Human IgG1 (Pro100-Lys330) N-terminus C-terminus
source short :
Sf 21 (baculovirus)
USD :
432 USD
alt names :
CD123, CD123 antigen, hIL3Ra, hIL-3Ra, IL-3 R alpha, IL-3 receptor subunit alpha, IL3R, IL3R alpha, IL-3R subunit alpha, IL3RA, IL-3RA, IL-3R-alpha, IL3RAY, IL3RX, IL3RY, interleukin 3 receptor, alpha (low affinity), interleukin-3 receptor subunit alpha, MGC34174
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.