Recombinant Mouse CD14 Fc Chimera Protein, CF | R&D Systems 982-CD-100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse CD14 Fc Chimera Protein, CF

catalog :

982-CD-100

quantity :

100 ug

price :

432 USD

citations: 6

Reference
Barbier V, Erbani J, Fiveash C, Davies J, Tay J, Tallack M, et al. Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance. Nat Commun. 2020;11:2042 pubmed publisher
Okamoto N, Mizote K, Honda H, Saeki A, Watanabe Y, Yamaguchi Miyamoto T, et al. Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex. J Biol Chem. 2017;292:15378-15394 pubmed publisher
Biedroń R, Peruń A, Jozefowski S. CD36 Differently Regulates Macrophage Responses to Smooth and Rough Lipopolysaccharide. PLoS ONE. 2016;11:e0153558 pubmed publisher
Hong C, Qiu X, Li Y, Huang Q, Zhong Z, Zhang Y, et al. Functional analysis of recombinant calreticulin fragment 39-272: implications for immunobiological activities of calreticulin in health and disease. J Immunol. 2010;185:4561-9 pubmed publisher
Brass D, Hollingsworth J, McElvania TeKippe E, Garantziotis S, Hossain I, Schwartz D. CD14 is an essential mediator of LPS-induced airway disease. Am J Physiol Lung Cell Mol Physiol. 2007;293:L77-83 pubmed
Bate C, Kempster S, Williams A. Prostaglandin D2 mediates neuronal damage by amyloid-beta or prions which activates microglial cells. Neuropharmacology. 2006;50:229-37 pubmed

product information

master code :

982-CD

SKU :

982-CD-100

product name :

Recombinant Mouse CD14 Fc Chimera Protein, CF

unit size :

100 ug

description :

The Recombinant Mouse CD14 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse CD14 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

CD14

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

85-95 kDa, reducing conditions

theoretical molecular weight :

61.8 kDa (monomer)

gene symbol :

Cd14

details of functionality :

Measured by its ability to enhance LPS-induced IL-6 secretion by mouse splenocytes. The ED50 for this effect is 0.4-2.4 ╡g/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q4FJP7

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse CD14 protein Mouse CD14 (Ala18-Pro345) Accession # Q4FJP7 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

NS0

USD :

432 USD

alt names :

CD14, CD14 antigen, CD14 molecule, monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.