product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse CD14 Fc Chimera Protein, CF
catalog :
982-CD-100
quantity :
100 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 6
Reference
Barbier V, Erbani J, Fiveash C, Davies J, Tay J, Tallack M, et al. Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance. Nat Commun. 2020;11:2042 pubmed publisher
Okamoto N, Mizote K, Honda H, Saeki A, Watanabe Y, Yamaguchi Miyamoto T, et al. Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex. J Biol Chem. 2017;292:15378-15394 pubmed publisher
Biedroń R, Peruń A, Jozefowski S. CD36 Differently Regulates Macrophage Responses to Smooth and Rough Lipopolysaccharide. PLoS ONE. 2016;11:e0153558 pubmed publisher
Hong C, Qiu X, Li Y, Huang Q, Zhong Z, Zhang Y, et al. Functional analysis of recombinant calreticulin fragment 39-272: implications for immunobiological activities of calreticulin in health and disease. J Immunol. 2010;185:4561-9 pubmed publisher
Brass D, Hollingsworth J, McElvania TeKippe E, Garantziotis S, Hossain I, Schwartz D. CD14 is an essential mediator of LPS-induced airway disease. Am J Physiol Lung Cell Mol Physiol. 2007;293:L77-83 pubmed
Bate C, Kempster S, Williams A. Prostaglandin D2 mediates neuronal damage by amyloid-beta or prions which activates microglial cells. Neuropharmacology. 2006;50:229-37 pubmed
product information
brand :
R&D Systems
master code :
982-CD
SKU :
982-CD-100
product name :
Recombinant Mouse CD14 Fc Chimera Protein, CF
unit size :
100 ug
seo description :
The Recombinant Mouse CD14 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse CD14 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
CD14
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
85-95 kDa, reducing conditions
theoretical molecular weight :
61.8 kDa (monomer)
gene symbol :
Cd14
details of functionality :
Measured by its ability to enhance LPS-induced IL-6 secretion by mouse splenocytes. The ED50 for this effect is 0.4-2.4 ╡g/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q4FJP7
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse CD14 Fc Chimera Protein, CF
USD :
432 USD
alt names :
CD14, CD14 antigen, CD14 molecule, monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.