Recombinant Human CXCL16 Protein | R&D Systems 976-CX-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CXCL16 Protein

catalog :

976-CX-025

quantity :

25 ug

price :

361 USD

more info or order :

R&D Systems product webpage

citations: 13

Reference
Savage T, Vincent R, Rae S, Huang L, Ahn A, Pu K, et al. Chemokines expressed by engineered bacteria recruit and orchestrate antitumor immunity. Sci Adv. 2023;9:eadc9436 pubmed publisher
Pallett L, Swadling L, Diniz M, Maini A, Schwabenland M, Gasull A, et al. Tissue CD14+CD8+ T cells reprogrammed by myeloid cells and modulated by LPS. Nature. 2023;614:334-342 pubmed publisher
Hiratsuka K, Miyoshi T, Kroll K, Gupta N, Valerius M, Ferrante T, et al. Organoid-on-a-chip model of human ARPKD reveals mechanosensing pathomechanisms for drug discovery. Sci Adv. 2022;8:eabq0866 pubmed publisher
Kim S, Chu Y, Misoi M, Suarez Almazor M, Tayar J, Lu H, et al. Distinct molecular and immune hallmarks of inflammatory arthritis induced by immune checkpoint inhibitors for cancer therapy. Nat Commun. 2022;13:1970 pubmed publisher
Prajzlerová K, Krystůfková O, Hanova P, Horváthová V, Gregová M, Pavelka K, et al. High miR-451 expression in peripheral blood mononuclear cells from subjects at risk of developing rheumatoid arthritis. Sci Rep. 2021;11:4719 pubmed publisher
Biasci D, Smoragiewicz M, Connell C, Wang Z, Gao Y, Thaventhiran J, et al. CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response. Proc Natl Acad Sci U S A. 2020;117:28960-28970 pubmed publisher
Ikeda T, Nishita M, Hoshi K, Honda T, Kakeji Y, Minami Y. Mesenchymal stem cell-derived CXCL16 promotes progression of gastric cancer cells by STAT3-mediated expression of Ror1. Cancer Sci. 2020;111:1254-1265 pubmed publisher
Krawczyk K, Nilsson H, Allaoui R, Lindgren D, Arvidsson M, Leandersson K, et al. Papillary renal cell carcinoma-derived chemerin, IL-8, and CXCL16 promote monocyte recruitment and differentiation into foam-cell macrophages. Lab Invest. 2017;97:1296-1305 pubmed publisher
Wente M, Gaida M, Mayer C, Michalski C, Haag N, Giese T, et al. Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma. Int J Oncol. 2008;33:297-308 pubmed
Smith C, Halvorsen B, Otterdal K, Waehre T, Yndestad A, Fevang B, et al. High levels and inflammatory effects of soluble CXC ligand 16 (CXCL16) in coronary artery disease: down-regulatory effects of statins. Cardiovasc Res. 2008;79:195-203 pubmed publisher
Held Feindt J, Rehmke B, Mentlein R, Hattermann K, Knerlich F, Hugo H, et al. Overexpression of CXCL16 and its receptor CXCR6/Bonzo promotes growth of human schwannomas. Glia. 2008;56:764-74 pubmed publisher
Facco M, Baesso I, Miorin M, Bortoli M, Cabrelle A, Boscaro E, et al. Expression and role of CCR6/CCL20 chemokine axis in pulmonary sarcoidosis. J Leukoc Biol. 2007;82:946-55 pubmed
Nakayama T, Shirane J, Hieshima K, Shibano M, Watanabe M, Jin Z, et al. Novel antiviral activity of chemokines. Virology. 2006;350:484-92 pubmed

product information

brand :

R&D Systems

master code :

976-CX

SKU :

976-CX-025

product name :

Recombinant Human CXCL16 Protein

unit size :

25 ug

seo description :

The Recombinant Human CXCL16 Protein from R&D Systems is derived from E. coli. The Recombinant Human CXCL16 Protein has been validated for the following applications: Bioactivity.

target :

CXCL16

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

10 kDa, reducing conditions

theoretical molecular weight :

10.2 kDa

gene symbol :

CXCL16

details of functionality :

Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with mouse CXCR6. Matloubian,áM. etáal . (2000) Nat. Immunol. 1 :298. The ED50 for this effect is 2.5-12 ng/mL.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q9H2A7.4

applications :

Bioactivity

source :

E. coli-derived Recombinant Human CXCL16 Protein

USD :

361 USD

alt names :

chemokine (C-X-C motif) ligand 16, CXC chemokine ligand 16, CXCL16, CXCLG16, Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, SCYB16, Small-inducible cytokine B16, SRPSOXC-X-C motif chemokine 16, SR-PSOXTransmembrane chemokine CXCL16

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage