product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat GITR Ligand/TNFSF18 Protein, CF
catalog :
9735-GL-050
quantity :
50 ug
price :
503 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
He Y, Pei Y, Liu K, Liu L, Tian Y, Li H, et al. GITR/GITRL reverse signalling modulates the proliferation of hepatic progenitor cells by recruiting ANXA2 to phosphorylate ERK1/2 and Akt. Cell Death Dis. 2022;13:297 pubmed publisher
product information
master code :
9735-GL
SKU :
9735-GL-050
product name :
Recombinant Rat GITR Ligand/TNFSF18 Protein, CF
unit size :
50 ug
description :
The Recombinant Rat GITR Ligand/TNFSF18 Protein, CF from R&D Systems is derived from NS0. The Recombinant Rat GITR Ligand/TNFSF18 Protein, CF has been validated for the following applications: Bioactivity.
target :
GITR Ligand/TNFSF18
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>85%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Rat
observed molecular weight :
19-22 kDa, reducing conditions
theoretical molecular weight :
16 kDa
details of functionality :
Measured by its ability to induce IL-8 secretion in HT1080 human fibrosarcoma cells transfected with rat GITR. The ED50 for this effect is 0.06-0.6 ╡g/mL in the presence of Mouse Anti-Hemagglutinin/HA Peptide Monoclonal Antibody (Catalog # MAB060 ).
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Rat GITR Ligand/TNFSF18 Protein Bioactivity
accessionNumbers :
XP_008767927
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived rat GITR Ligand/TNFSF18 protein Thr74-Ser200, with a N-terminal HA-tag
source short :
NS0
USD :
503 USD
alt names :
Activation-inducible TNF-related ligand, AITRL, AITRLMGC138237, GITRL, GITRLglucocorticoid-induced TNFR-related protein ligand, Glucocorticoid-induced TNF-related ligand, hGITRLGITR ligand, TL6AITR ligand, TNFSF18, tumor necrosis factor (ligand) superfamily, member 18, tumor necrosis factor ligand superfamily member 18
storage :
12 months from date of receipt, <= -20 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, <= -20 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.