product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human MCAM/CD146 Fc Chimera Protein, CF
catalog :
9709-MA-050
quantity :
50 ug
price :
503 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Abu El Asrar A, Nawaz M, Ahmad A, Siddiquei M, Allegaert E, Gikandi P, et al. CD146/Soluble CD146 Pathway Is a Novel Biomarker of Angiogenesis and Inflammation in Proliferative Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2021;62:32 pubmed publisher
Malara N, Trunzo V, Musolino G, Aprigliano S, Rotta G, Macrina L, et al. Soluble CD54 induces human endothelial cells ex vivo expansion useful for cardiovascular regeneration and tissue engineering application. Int J Cardiol Heart Vasc. 2015;6:48-53 pubmed publisher
product information
master code :
9709-MA
SKU :
9709-MA-050
product name :
Recombinant Human MCAM/CD146 Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Human MCAM/CD146 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human MCAM/CD146 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
MCAM/CD146
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
108-124 kDa, reducing condtions
theoretical molecular weight :
87 kDa
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human MCAM/CD146 Fc Chimera is immobilized at 1 ╡g/mL, 100 ╡L/well, it binds Recombinant Human Galectin-3 (Catalog # 8259-GA ). The concentration of Recombinant Human Galectin-3 that produces 50% of the optimal binding response is 0.25-1.25 ╡g/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Human MCAM/CD146 Fc Chimera Protein Bioactivity
accessionNumbers :
AAA20922
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived human MCAM/CD146 protein Human MCAM/CD146 (Val24-Gly559) Accession # AAA20922 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus
source short :
NS0
USD :
503 USD
alt names :
CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, L-Gicerin, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18, MUC18Gicerin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.