Recombinant Mouse TfR (Transferrin R) Protein, CF | R&D Systems 9706-TR-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse TfR (Transferrin R) Protein, CF

catalog :

9706-TR-050

quantity :

50 ug

price :

443 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Crook Z, Sevilla G, Young P, Girard E, Phi T, Howard M, et al. CYpHER: Catalytic extracellular targeted protein degradation with high potency and durable effect. bioRxiv. 2024;: pubmed publisher
Desjardins C, Yao M, Hall J, O Donnell E, Venkatesan R, Spring S, et al. Enhanced exon skipping and prolonged dystrophin restoration achieved by TfR1-targeted delivery of antisense oligonucleotide using FORCE conjugation in mdx mice. Nucleic Acids Res. 2022;50:11401-11414 pubmed publisher
Castellanos D, Sun J, Yang J, Ou W, Zambon A, Pardridge W, et al. Acute and Chronic Dosing of a High-Affinity Rat/Mouse Chimeric Transferrin Receptor Antibody in Mice. Pharmaceutics. 2020;12: pubmed publisher

product information

brand :

R&D Systems

master code :

9706-TR

SKU :

9706-TR-050

product name :

Recombinant Mouse TfR (Transferrin R) Protein, CF

unit size :

50 ug

seo description :

The Recombinant Mouse TfR (Transferrin R) Protein, CF from R&D Systems is derived from CHO. The Recombinant Mouse TfR (Transferrin R) Protein, CF has been validated for the following applications: Bioactivity.

target :

TfR (Transferrin R)

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Mouse

observed molecular weight :

75-86 kDa (major) and 133-157 kDa (minor), under reducing conditions.

theoretical molecular weight :

77 kDa

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Mouse TfR (Transferrin R) (Catalog # 9706-TR) is immobilized at 5 ╡g/mL (100 ╡L/well), Biotinylated Mouse Holo-Transferrin binds with an ED50 of 20.0-160 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Mouse TfR (Transferrin R) Protein Binding Activity

accessionNumbers :

Q62351

applications :

Bioactivity

source :

CHO-derived Recombinant Mouse TfR (Transferrin R) Protein, CF

USD :

443 USD

alt names :

CD71, CD71 antigen, CD71TRFR, p90, T9, TfR, TfR (TransferrinR), TFR1, TFRC, TR, transferrin receptor (p90, CD71), transferrin receptor protein 1, Trfr

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage