Recombinant Human Angiopoietin-4 Protein | R&D Systems 964-AN product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Angiopoietin-4 Protein

catalog :

964-AN

quantity :

25 ug

price :

389 USD

citations: 4

Reference
Elamaa H, Kihlström M, Kapiainen E, Kaakinen M, Miinalainen I, Ragauskas S, et al. Angiopoietin-4-dependent venous maturation and fluid drainage in the peripheral retina. elife. 2018;7: pubmed publisher
Mamer S, Chen S, Weddell J, Palasz A, Wittenkeller A, Kumar M, et al. Discovery of High-Affinity PDGF-VEGFR Interactions: Redefining RTK Dynamics. Sci Rep. 2017;7:16439 pubmed publisher
Brunckhorst M, Xu Y, Lu R, Yu Q. Angiopoietins promote ovarian cancer progression by establishing a procancer microenvironment. Am J Pathol. 2014;184:2285-96 pubmed publisher
Brunckhorst M, Wang H, Lu R, Yu Q. Angiopoietin-4 promotes glioblastoma progression by enhancing tumor cell viability and angiogenesis. Cancer Res. 2010;70:7283-93 pubmed publisher

product information

brand :

R&D Systems

master code :

964-AN

SKU :

964-AN-025

product name :

Recombinant Human Angiopoietin-4 Protein

description :

The Recombinant Human Angiopoietin-4 Protein from R&D Systems is derived from NS0. The Recombinant Human Angiopoietin-4 Protein has been validated for the following applications: Binding Activity.

target :

Angiopoietin-4

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Tris-Citrate and NaCl with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>85%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

60-100 kDa, reducing conditions

theoretical molecular weight :

57 kDa (monomer)

gene symbol :

ANGPT4

details of functionality :

Measured by its ability to compete with biotinylated rhAng-2 for binding to immobilized Tie-2/Fc Chimera in a functional ELISA. Compared to rmAngiopoietin-3, rhAngiopoietin-4 is less effective in this competitive assay.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

964-AN

accessionNumbers :

Q9Y264

applications :

Binding Activity

source :

Mouse myeloma cell line, NS0-derived human Angiopoietin-4 protein Human Ang-4 (Gln23 - Ile503) or (Gln24 - Ile503) Accession # Q9Y264 IEGR GGGSGGGSGGGS 10-His tag N-terminus C-terminus

2020 USD :

389

2021 USD :

389 USD

alt names :

AGP4, ANG3, ANG-3, ANG-4, ANG4angiopoietin-3, angiopoietin 4, Angiopoietin-3, angiopoietin-4, ANGPT4, dJ824F16.2 (angiopoietin 4), MGC138181, MGC138183

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.