product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Angiopoietin-4 Protein
catalog :
964-AN-025
quantity :
25 ug
price :
491 USD
more info or order :
citations: 6
Reference
Hou Q, Jia J, Lin J, Zhu L, Xie S, Yu Q, et al. Bacillus subtilis programs the differentiation of intestinal secretory lineages to inhibit Salmonella infection. Cell Rep. 2022;40:111416 pubmed publisher
Mamer S, Wittenkeller A, Imoukhuede P. VEGF-A splice variants bind VEGFRs with differential affinities. Sci Rep. 2020;10:14413 pubmed publisher
Elamaa H, Kihlström M, Kapiainen E, Kaakinen M, Miinalainen I, Ragauskas S, et al. Angiopoietin-4-dependent venous maturation and fluid drainage in the peripheral retina. elife. 2018;7: pubmed publisher
Mamer S, Chen S, Weddell J, Palasz A, Wittenkeller A, Kumar M, et al. Discovery of High-Affinity PDGF-VEGFR Interactions: Redefining RTK Dynamics. Sci Rep. 2017;7:16439 pubmed publisher
Brunckhorst M, Xu Y, Lu R, Yu Q. Angiopoietins promote ovarian cancer progression by establishing a procancer microenvironment. Am J Pathol. 2014;184:2285-96 pubmed publisher
Brunckhorst M, Wang H, Lu R, Yu Q. Angiopoietin-4 promotes glioblastoma progression by enhancing tumor cell viability and angiogenesis. Cancer Res. 2010;70:7283-93 pubmed publisher
product information
brand :
R&D Systems
master code :
964-AN
SKU :
964-AN-025
product name :
Recombinant Human Angiopoietin-4 Protein
unit size :
25 ug
seo description :
The Recombinant Human Angiopoietin-4 Protein from R&D Systems is derived from NS0. The Recombinant Human Angiopoietin-4 Protein has been validated for the following applications: Binding Activity.
target :
Angiopoietin-4
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in Tris-Citrate and NaCl with BSA as a carrier protein.
conjugate :
Unconjugated
dilution :
Binding Activity
purity :
>85%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
60-100 kDa, reducing conditions
theoretical molecular weight :
57 kDa (monomer)
gene symbol :
ANGPT4
details of functionality :
Measured by its ability to compete with biotinylated rhAng-2 for binding to immobilized Tie-2/Fc Chimera in a functional ELISA. Compared to rmAngiopoietin-3, rhAngiopoietin-4 is less effective in this competitive assay.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q9Y264
applications :
Binding Activity
source :
NS0-derived Recombinant Human Angiopoietin-4 Protein
USD :
491 USD
alt names :
AGP4, ANG3, ANG-3, ANG-4, ANG4angiopoietin-3, angiopoietin 4, Angiopoietin-3, angiopoietin-4, ANGPT4, dJ824F16.2 (angiopoietin 4), MGC138181, MGC138183
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.