Recombinant Human Erythropoietin R Fc Chimera Protein, CF | R&D Systems 963-ER product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Erythropoietin R Fc Chimera Protein, CF

catalog :

963-ER

quantity :

50 ug

price :

389 USD

citations: 3

Reference
Burrill D, Vernet A, Collins J, Silver P, Way J. Targeted erythropoietin selectively stimulates red blood cell expansion in vivo. Proc Natl Acad Sci U S A. 2016;113:5245-50 pubmed publisher
Khankin E, Mutter W, Tamez H, Yuan H, Karumanchi S, Thadhani R. Soluble erythropoietin receptor contributes to erythropoietin resistance in end-stage renal disease. PLoS ONE. 2010;5:e9246 pubmed publisher
Lupia E, Bosco O, Goffi A, Poletto C, Locatelli S, Spatola T, et al. Thrombopoietin contributes to enhanced platelet activation in cigarette smokers. Atherosclerosis. 2010;210:314-9 pubmed publisher

product information

brand :

R&D Systems

master code :

963-ER

SKU :

963-ER-050

product name :

Recombinant Human Erythropoietin R Fc Chimera Protein, CF

description :

The Recombinant Human Erythropoietin R Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Erythropoietin R Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

Erythropoietin R

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS, EDTA and CHAPS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

55-60 kDa, reducing conditions

theoretical molecular weight :

51.4 kDa (monomer)

gene symbol :

EPOR

details of functionality :

Measured by its ability to inhibit Epo-dependent proliferation of TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 1-4 ng/mL in the presence of 0.1 U/mL of recombinant human Epo.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

963-ER

accessionNumbers :

P19235

applications :

Bioactivity

source :

Mouse myeloma cell line, NS0-derived human Erythropoietin R protein Human Epo R (Ala25-Pro250) Accession # P19235 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

2020 USD :

389

2021 USD :

389 USD

alt names :

EpoR, EPO-R, erythropoietin receptor, MGC138358

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.