Recombinant Human Fc gamma RIIA/CD32a (H167) Protein, CF | R&D Systems 9595-CD-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Fc gamma RIIA/CD32a (H167) Protein, CF

catalog :

9595-CD-050

quantity :

50 ug

price :

443 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Torchia J, Tavares A, Carstensen L, Chen D, Huang J, Xiao T, et al. Optimized ACE2 decoys neutralize antibody-resistant SARS-CoV-2 variants through functional receptor mimicry and treat infection in vivo. Sci Adv. 2022;8:eabq6527 pubmed publisher
Bates T, Lu P, Kang Y, Schoen D, Thornton M, McBride S, et al. BNT162b2-induced neutralizing and non-neutralizing antibody functions against SARS-CoV-2 diminish with age. Cell Rep. 2022;41:111544 pubmed publisher

product information

master code :

9595-CD

SKU :

9595-CD-050

product name :

Recombinant Human Fc gamma RIIA/CD32a (H167) Protein, CF

unit size :

50 ug

description :

The Recombinant Human Fc gamma RIIA/CD32a (H167) Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Fc gamma RIIA/CD32a (H167) Protein, CF has been validated for the following applications: Bioactivity.

target :

Fc gamma RIIA/CD32a

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

25-37 kDa, reducing conditions

theoretical molecular weight :

22 kDa

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human Fc gamma RIIA/CD32a (H167) is coated at 1 ╡g/mL, 100 ╡L/well, it binds to human IgG with an ED50 of 0.25-1.25 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Human Fc gamma RIIA/CD32a (H167) Protein Bioactivity

accessionNumbers :

P12318-1

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human Fc gamma RIIA/CD32a protein Gln34-Ile218, with a C-terminal 10-His tag

source short :

NS0

USD :

443 USD

alt names :

CD32 antigen, CD32A, CD32MGC23887, CDw32fc-gamma-RIIa, Fc fragment of IgG, low affinity IIa, receptor (CD32), Fc fragment of IgG, low affinity IIa, receptor for (CD32), FCG2, Fc-gamma RII-a, Fc-gamma-RIIa, FcGR, FCGR2, FCGR2A, FCGR2A1, FcgRIIA, FcRII-a, FCRIIA, IGFR2MGC30032, IgG Fc receptor II-a, Immunoglobulin G Fc receptor II, low affinity immunoglobulin gamma Fc region receptor II-a

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage