Recombinant Mouse Erythropoietin/EPO Protein | R&D Systems 959-ME-010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Erythropoietin/EPO Protein

catalog :

959-ME-010

quantity :

10 ug

price :

432 USD

citations: 20

Reference
Lara Astiaso D, Go xf1 i Salaverri A, Mendieta Esteban J, Narayan N, Del Valle C, Gross T, et al. In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesis. Nat Genet. 2023;55:1542-1554 pubmed publisher
Feng Y, Borosha S, Ratri A, Lee E, Wang H, Fields T, et al. DOT1L Methyltransferase Regulates Calcium Influx in Erythroid Progenitor Cells in Response to Erythropoietin. Int J Mol Sci. 2022;23: pubmed publisher
Cardoso A, Martins A, Maceiras A, Liu W, Castro I, Castro A, et al. Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis. Cell Rep. 2021;37:109887 pubmed publisher
Bertho J, Kereselidze D, Manens L, Culeux C, Magneron V, Surette J, et al. Hto, Tritiated Amino Acid Exposure and External Exposure Induce Differential Effects on Hematopoiesis and Iron Metabolism. Sci Rep. 2019;9:19919 pubmed publisher
Mayers S, Moço P, Maqbool T, Silva P, Kilkenny D, Audet J. Establishment of an erythroid progenitor cell line capable of enucleation achieved with an inducible c-Myc vector. BMC Biotechnol. 2019;19:21 pubmed publisher
Funk N, Munz M, Ott T, Brockmann K, Wenninger Weinzierl A, Kühn R, et al. The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4. Sci Rep. 2019;9:4515 pubmed publisher
Yashiro M, Ohya M, Mima T, Ueda Y, Nakashima Y, Kawakami K, et al. FGF23 modulates the effects of erythropoietin on gene expression in renal epithelial cells. Int J Nephrol Renovasc Dis. 2018;11:125-136 pubmed publisher
Xu T, Jin H, Lao Y, Wang P, Zhang S, Ruan H, et al. Administration of erythropoietin prevents bone loss in osteonecrosis of the femoral head in mice. Mol Med Rep. 2017;16:8755-8762 pubmed publisher
Takagishi T, Takehara M, Seike S, Miyamoto K, Kobayashi K, Nagahama M. Clostridium perfringens α-toxin impairs erythropoiesis by inhibition of erythroid differentiation. Sci Rep. 2017;7:5217 pubmed publisher
Laroque A, Min oo G, Tam M, Ponka P, Stevenson M, Gros P. The mouse Char10 locus regulates severity of pyruvate kinase deficiency and susceptibility to malaria. PLoS ONE. 2017;12:e0177818 pubmed publisher
Pathipati P, Ferriero D. The Differential Effects of Erythropoietin Exposure to Oxidative Stress on Microglia and Astrocytes in vitro. Dev Neurosci. 2017;39:310-322 pubmed publisher
Pardi N, Secreto A, Shan X, Debonera F, Glover J, Yi Y, et al. Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge. Nat Commun. 2017;8:14630 pubmed publisher
Mucci A, Kunkiel J, Suzuki T, Brennig S, Glage S, Kühnel M, et al. Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency. Stem Cell Reports. 2016;7:292-305 pubmed publisher
Luyten A, Zang C, Liu X, Shivdasani R. Active enhancers are delineated de novo during hematopoiesis, with limited lineage fidelity among specified primary blood cells. Genes Dev. 2014;28:1827-39 pubmed publisher
Kim E, Miyake B, Aggarwal M, Voetlause R, Griffith M, Zavazava N. Embryonic stem cell-derived haematopoietic progenitor cells down-regulate the CD3 ? chain on T cells, abrogating alloreactive T cells. Immunology. 2014;142:421-30 pubmed publisher
Grover A, Mancini E, Moore S, Mead A, Atkinson D, Rasmussen K, et al. Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate. J Exp Med. 2014;211:181-8 pubmed publisher
Yamamizu K, Piao Y, Sharov A, Zsiros V, Yu H, Nakazawa K, et al. Identification of transcription factors for lineage-specific ESC differentiation. Stem Cell Reports. 2013;1:545-59 pubmed publisher
Keil E, Finkenstädt D, Wufka C, Trilling M, Liebfried P, Strobl B, et al. Important scaffold function of the Janus kinase 2 uncovered by a novel mouse model harboring a Jak2 activation-loop mutation. Blood. 2014;123:520-9 pubmed publisher
Angelillo Scherrer A, Burnier L, Lambrechts D, Fish R, Tjwa M, Plaisance S, et al. Role of Gas6 in erythropoiesis and anemia in mice. J Clin Invest. 2008;118:583-96 pubmed publisher
Rajesh D, Chinnasamy N, Mitalipov S, Wolf D, Slukvin I, Thomson J, et al. Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells. 2007;25:490-9 pubmed

product information

master code :

959-ME

SKU :

959-ME-010

product name :

Recombinant Mouse Erythropoietin/EPO Protein

unit size :

10 ug

description :

The Recombinant Mouse Erythropoietin/EPO Protein from R&D Systems is derived from NS0. The Recombinant Mouse Erythropoietin/EPO Protein has been validated for the following applications: Bioactivity.

target :

Erythropoietin/EPO

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

36 kDa, reducing conditions

theoretical molecular weight :

18.6 kDa

gene symbol :

Epo

details of functionality :

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 0.4-2 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q0VED9

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse Erythropoietin/EPO protein Ala27-Arg192

source short :

NS0

USD :

432 USD

alt names :

ECYT5, EP, EPO, epoetin, erythropoietin, MGC138142, MVCD2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.