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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Erythropoietin/EPO Protein
catalog :
959-ME-010
quantity :
10 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 20
Reference
Lara Astiaso D, Go xf1 i Salaverri A, Mendieta Esteban J, Narayan N, Del Valle C, Gross T, et al. In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesis. Nat Genet. 2023;55:1542-1554 pubmed publisher
Feng Y, Borosha S, Ratri A, Lee E, Wang H, Fields T, et al. DOT1L Methyltransferase Regulates Calcium Influx in Erythroid Progenitor Cells in Response to Erythropoietin. Int J Mol Sci. 2022;23: pubmed publisher
Cardoso A, Martins A, Maceiras A, Liu W, Castro I, Castro A, et al. Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis. Cell Rep. 2021;37:109887 pubmed publisher
Bertho J, Kereselidze D, Manens L, Culeux C, Magneron V, Surette J, et al. Hto, Tritiated Amino Acid Exposure and External Exposure Induce Differential Effects on Hematopoiesis and Iron Metabolism. Sci Rep. 2019;9:19919 pubmed publisher
Mayers S, Moço P, Maqbool T, Silva P, Kilkenny D, Audet J. Establishment of an erythroid progenitor cell line capable of enucleation achieved with an inducible c-Myc vector. BMC Biotechnol. 2019;19:21 pubmed publisher
Funk N, Munz M, Ott T, Brockmann K, Wenninger Weinzierl A, Kühn R, et al. The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4. Sci Rep. 2019;9:4515 pubmed publisher
Yashiro M, Ohya M, Mima T, Ueda Y, Nakashima Y, Kawakami K, et al. FGF23 modulates the effects of erythropoietin on gene expression in renal epithelial cells. Int J Nephrol Renovasc Dis. 2018;11:125-136 pubmed publisher
Xu T, Jin H, Lao Y, Wang P, Zhang S, Ruan H, et al. Administration of erythropoietin prevents bone loss in osteonecrosis of the femoral head in mice. Mol Med Rep. 2017;16:8755-8762 pubmed publisher
Takagishi T, Takehara M, Seike S, Miyamoto K, Kobayashi K, Nagahama M. Clostridium perfringens α-toxin impairs erythropoiesis by inhibition of erythroid differentiation. Sci Rep. 2017;7:5217 pubmed publisher
Laroque A, Min oo G, Tam M, Ponka P, Stevenson M, Gros P. The mouse Char10 locus regulates severity of pyruvate kinase deficiency and susceptibility to malaria. PLoS ONE. 2017;12:e0177818 pubmed publisher
Pathipati P, Ferriero D. The Differential Effects of Erythropoietin Exposure to Oxidative Stress on Microglia and Astrocytes in vitro. Dev Neurosci. 2017;39:310-322 pubmed publisher
Pardi N, Secreto A, Shan X, Debonera F, Glover J, Yi Y, et al. Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge. Nat Commun. 2017;8:14630 pubmed publisher
Mucci A, Kunkiel J, Suzuki T, Brennig S, Glage S, Kühnel M, et al. Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency. Stem Cell Reports. 2016;7:292-305 pubmed publisher
Luyten A, Zang C, Liu X, Shivdasani R. Active enhancers are delineated de novo during hematopoiesis, with limited lineage fidelity among specified primary blood cells. Genes Dev. 2014;28:1827-39 pubmed publisher
Kim E, Miyake B, Aggarwal M, Voetlause R, Griffith M, Zavazava N. Embryonic stem cell-derived haematopoietic progenitor cells down-regulate the CD3 ? chain on T cells, abrogating alloreactive T cells. Immunology. 2014;142:421-30 pubmed publisher
Grover A, Mancini E, Moore S, Mead A, Atkinson D, Rasmussen K, et al. Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate. J Exp Med. 2014;211:181-8 pubmed publisher
Yamamizu K, Piao Y, Sharov A, Zsiros V, Yu H, Nakazawa K, et al. Identification of transcription factors for lineage-specific ESC differentiation. Stem Cell Reports. 2013;1:545-59 pubmed publisher
Keil E, Finkenstädt D, Wufka C, Trilling M, Liebfried P, Strobl B, et al. Important scaffold function of the Janus kinase 2 uncovered by a novel mouse model harboring a Jak2 activation-loop mutation. Blood. 2014;123:520-9 pubmed publisher
Angelillo Scherrer A, Burnier L, Lambrechts D, Fish R, Tjwa M, Plaisance S, et al. Role of Gas6 in erythropoiesis and anemia in mice. J Clin Invest. 2008;118:583-96 pubmed publisher
Rajesh D, Chinnasamy N, Mitalipov S, Wolf D, Slukvin I, Thomson J, et al. Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells. 2007;25:490-9 pubmed
product information
brand :
R&D Systems
master code :
959-ME
SKU :
959-ME-010
product name :
Recombinant Mouse Erythropoietin/EPO Protein
unit size :
10 ug
seo description :
The Recombinant Mouse Erythropoietin/EPO Protein from R&D Systems is derived from NS0. The Recombinant Mouse Erythropoietin/EPO Protein has been validated for the following applications: Bioactivity.
target :
Erythropoietin/EPO
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
36 kDa, reducing conditions
theoretical molecular weight :
18.6 kDa
gene symbol :
Epo
details of functionality :
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 0.4-2 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q0VED9
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse Erythropoietin/EPO Protein
USD :
432 USD
alt names :
ECYT5, EP, EPO, epoetin, erythropoietin, MGC138142, MVCD2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.