Recombinant Mouse DPPIV/CD26 Protein, CF | R&D Systems 954-SE-010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse DPPIV/CD26 Protein, CF

catalog :

954-SE-010

quantity :

10 ug

price :

456 USD

citations: 6

Reference
Madsen T, Hansen L, Hintze J, Ye Z, Jebari S, Andersen D, et al. An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles. Nat Commun. 2020;11:4033 pubmed publisher
Sarker M, Lee J, Lee D, Chun K, Jun H. Attenuation of diabetic kidney injury in DPP4-deficient rats; role of GLP-1 on the suppression of AGE formation by inducing glyoxalase 1. Aging (Albany NY). 2020;12:593-610 pubmed publisher
Baumeier C, Schlüter L, Saussenthaler S, Laeger T, Rödiger M, Alaze S, et al. Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease. Mol Metab. 2017;6:1254-1263 pubmed publisher
Ambrosi T, Scialdone A, Graja A, Gohlke S, Jank A, Bocian C, et al. Adipocyte Accumulation in the Bone Marrow during Obesity and Aging Impairs Stem Cell-Based Hematopoietic and Bone Regeneration. Cell Stem Cell. 2017;20:771-784.e6 pubmed publisher
Pang Z, Nakagami H, Osako M, Koriyama H, Nakagami F, Tomioka H, et al. Therapeutic vaccine against DPP4 improves glucose metabolism in mice. Proc Natl Acad Sci U S A. 2014;111:E1256-63 pubmed publisher
Yasuda N, Nagakura T, Inoue T, Yamazaki K, Katsutani N, Takenaka O, et al. E3024, 3-but-2-ynyl-5-methyl-2-piperazin-1-yl-3,5-dihydro-4H-imidazo[4,5-d]pyridazin-4-one tosylate, is a novel, selective and competitive dipeptidyl peptidase-IV inhibitor. Eur J Pharmacol. 2006;548:181-7 pubmed

product information

master code :

954-SE

SKU :

954-SE-010

product name :

Recombinant Mouse DPPIV/CD26 Protein, CF

unit size :

10 ug

description :

The Recombinant Mouse DPPIV/CD26 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse DPPIV/CD26 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

DPPIV/CD26

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Mouse

observed molecular weight :

105 kDa, reducing conditions

theoretical molecular weight :

86 kDa

gene symbol :

Dpp4

details of functionality :

Measured by its ability to cleave the fluorogenic peptide substrate, Gly-Pro-7-amido-4-methylcoumarin (GP-AMC). The specific activity is 2,500 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P28843

applications :

Enzyme Activity

source long :

Mouse myeloma cell line, NS0-derived mouse DPPIV/CD26 protein Ser29-His760, with a C-terminal 9-His tag

source short :

NS0

USD :

456 USD

alt names :

ADABP, ADCP-2, ADCP2DPP IV, Adenosine deaminase complexing protein 2TP103, CD26, CD26 antigen, CD26T-cell activation antigen CD26, dipeptidyl peptidase 4, Dipeptidyl peptidase IV, dipeptidylpeptidase 4, dipeptidyl-peptidase 4, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2), DPP4, DPPIV, EC 3.4.14.5

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.