This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Cathepsin L Protein, CF
catalog :
952-CY
quantity :
10 ug
price :
339 USD
citations: 17
Reference |
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Burster T, Marin Esteban V, Boehm B, Dunn S, Rotzschke O, Falk K, et al. Design of protease-resistant myelin basic protein-derived peptides by cleavage site directed amino acid substitutions. Biochem Pharmacol. 2007;74:1514-23 pubmed
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Methot N, Rubin J, Guay D, Beaulieu C, Ethier D, Reddy T, et al. Inhibition of the activation of multiple serine proteases with a cathepsin C inhibitor requires sustained exposure to prevent pro-enzyme processing. J Biol Chem. 2007;282:20836-46 pubmed
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Cheng T, Hitomi K, van Vlijmen Willems I, de Jongh G, Yamamoto K, Nishi K, et al. Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification. J Biol Chem. 2006;281:15893-9 pubmed
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Gocheva V, Zeng W, Ke D, Klimstra D, Reinheckel T, Peters C, et al. Distinct roles for cysteine cathepsin genes in multistage tumorigenesis. Genes Dev. 2006;20:543-56 pubmed
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product information
brand :
R&D Systems
master code :
952-CY
SKU :
952-CY-010
product name :
Recombinant Human Cathepsin L Protein, CF
description :
The Recombinant Human Cathepsin L Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Cathepsin L Protein, CF has been validated for the following applications: Enzyme Activity.
target :
Cathepsin L
category :
Proteins and Enzymes
unit size :
10 ug
buffer :
Supplied as a 0.2 µm filtered solution in Sodium Acetate and NaCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
36 kDa, reducing conditions
theoretical molecular weight :
26 kDa
gene symbol :
CTSL
details of functionality :
Measured by its ability to cleave the fluorogenic peptide substrate Z-LR-AMC (Catalog # ES008 ). The specific activity is 25,000 pmol/min/µg, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
catalog number base :
952-CY
accessionNumbers :
P07711
applications :
Enzyme Activity
source :
Mouse myeloma cell line, NS0-derived human Cathepsin L protein Glu113-Val333 & Ala114-Val333, both with a C-terminal 6-His tag
2020 USD :
339
2021 USD :
339 USD
alt names :
cathepsin L, cathepsin L1, CATL, CTSL, CTSL1, CTSLEC 3.4.22.15, EC 3.4.22, FLJ31037, Major excreted protein, MEP
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.
company information

R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
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