Recombinant Mouse SPARC Protein, CF | R&D Systems 942-SP-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse SPARC Protein, CF

catalog :

942-SP-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Hu L, He F, Huang M, Zhao Q, Cheng L, Said N, et al. SPARC promotes insulin secretion through down-regulation of RGS4 protein in pancreatic β cells. Sci Rep. 2020;10:17581 pubmed publisher
John B, Naczki C, Patel C, Ghoneum A, Qasem S, Salih Z, et al. Regulation of the bi-directional cross-talk between ovarian cancer cells and adipocytes by SPARC. Oncogene. 2019;38:4366-4383 pubmed publisher
Jones E, Bernardinelli Y, Zarruk J, Chierzi S, Murai K. SPARC and GluA1-Containing AMPA Receptors Promote Neuronal Health Following CNS Injury. Front Cell Neurosci. 2018;12:22 pubmed publisher
Melouane A, Carbonell A, Yoshioka M, Puymirat J, St Amand J. Implication of SPARC in the modulation of the extracellular matrix and mitochondrial function in muscle cells. PLoS ONE. 2018;13:e0192714 pubmed publisher
Luo Z, Zhou Y, Luo P, Zhao Q, Xiao N, Yu Y, et al. SPARC deficiency affects bone marrow stromal function, resulting in impaired B lymphopoiesis. J Leukoc Biol. 2014;96:73-82 pubmed publisher
Jones E, Bernardinelli Y, Tse Y, Chierzi S, Wong T, Murai K. Astrocytes control glutamate receptor levels at developing synapses through SPARC-beta-integrin interactions. J Neurosci. 2011;31:4154-65 pubmed publisher

product information

brand :

R&D Systems

master code :

942-SP

SKU :

942-SP-050

product name :

Recombinant Mouse SPARC Protein, CF

unit size :

50 ug

seo description :

The Recombinant Mouse SPARC Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse SPARC Protein, CF has been validated for the following applications: Bioactivity.

target :

SPARC

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

42 kDa, reducing conditions

theoretical molecular weight :

34 kDa

gene symbol :

Sparc

details of functionality :

Measured by its ability to inhibit the cell growth of Mv1Lu mink lung epithelial cells. Schiemann,áB.J. etáal . (2003) Mol. Biol. Cell. 14 :3977. The ED50 for this effect is 0.6-2.4á╡g/mL. Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P07214

applications :

Bioactivity

source :

NS0-derived Recombinant Mouse SPARC Protein, CF

USD :

432 USD

alt names :

Basement-membrane protein 40, BM-40, ONcysteine-rich protein, osteonectin, Secreted protein acidic and rich in cysteine, secreted protein, acidic, cysteine-rich (osteonectin)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage