Recombinant Cynomolgus VISTA/B7-H5 Fc Chimera Protein, CF | R&D Systems 9408-B7-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Cynomolgus VISTA/B7-H5 Fc Chimera Protein, CF

catalog :

9408-B7-100

quantity :

100 ug

price :

443 USD

more info or order :

R&D Systems product webpage

citations: 1

Reference
Mehta N, Maddineni S, Kelly R, Lee R, Hunter S, Silberstein J, et al. An engineered antibody binds a distinct epitope and is a potent inhibitor of murine and human VISTA. Sci Rep. 2020;10:15171 pubmed publisher

product information

master code :

9408-B7

SKU :

9408-B7-100

product name :

Recombinant Cynomolgus VISTA/B7-H5 Fc Chimera Protein, CF

unit size :

100 ug

description :

The Recombinant Cynomolgus VISTA/B7-H5 Fc Chimera Protein, CF from R&D Systems is derived from HEK293. The Recombinant Cynomolgus VISTA/B7-H5 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

VISTA/B7-H5/PD-1H

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Cynomolgus Monkey

observed molecular weight :

62-71 kDa, reducing conditions

theoretical molecular weight :

45 kDa

details of functionality :

Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T lymphocytes. The ED50 for this effect is 0.6-3 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Cynomolgus VISTA/B7-H5 Fc Chimera Protein Bioactivity

accessionNumbers :

XP_005565644

applications :

Bioactivity

source long :

Human embryonic kidney cell, HEK293-derived cynomolgus monkey VISTA/B7-H5/PD-1H protein Cynomolgus Monkey VISTA/B7-H5 (Phe33-Ala194) Accession # XP_005565644 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

HEK293

USD :

443 USD

alt names :

4632428N05Rik, B7H5, B7-H5, C10orf54, chromosome 10 open reading frame 54, Dies1, Gi24, PD1H, PD-1H, platelet receptor Gi24, PP2135, SISP1, stress induced secreted protein 1, VSIR

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage