product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Integrin alpha 3 beta 1/VLA-3 Protein, CF
catalog :
9374-A3-050
quantity :
50 ug
price :
612 USD
more info or order :
citations: 2
Reference
Cegarra C, Cameron B, Chaves C, Dabdoubi T, Do T, Gen xea t B, et al. An innovative strategy to identify new targets for delivering antibodies to the brain has led to the exploration of the integrin family. PLoS ONE. 2022;17:e0274667 pubmed publisher
Brehs M, Pötgens A, Steitz J, Thewes K, Schwarz J, Conibear A, et al. Synthetic integrin-binding immune stimulators target cancer cells and prevent tumor formation. Sci Rep. 2017;7:17592 pubmed publisher
product information
master code :
9374-A3
SKU :
9374-A3-050
product name :
Recombinant Mouse Integrin alpha 3 beta 1/VLA-3 Protein, CF
unit size :
50 ug
description :
The Recombinant Mouse Integrin alpha 3 beta 1/VLA-3 Protein, CF from R&D Systems is derived from CHO. The Recombinant Mouse Integrin alpha 3 beta 1/VLA-3 Protein, CF has been validated for the following applications: Bioactivity.
target :
Integrin alpha 3 beta 1/VLA-3
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Mouse
observed molecular weight :
102-163 kDa, reducing conditions
theoretical molecular weight :
116 kDa (Integrin alpha 3) 86 kDa (Integrin ▀1)
details of functionality :
Measured by its binding ability in a functional ELISA. When Cultrex« Mouse Laminin I (Catalog # 3400-010-01 ) is coated at 2 ╡g/mL, Recombinant alpha 3▀1/VLA-3 binds with an ED50 = 150-900 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Mouse Integrin alpha 3 beta 1/VLA-3 Protein Bioactivity
accessionNumbers :
Q62470-1 (Integrin alpha 3) P09055-1 (Integrin ▀1)
applications :
Bioactivity
source long :
Chinese Hamster Ovary cell line, CHO-derived mouse Integrin alpha 3 beta 1/VLA-3 protein Mouse Integrin alpha 3 (Phe33-Glu993) Accession # Q62470-1 His-Pro GGGSGGGS Acidic Tail 6-His tag Mouse Integrin ▀1 (Gln21-Asp728) Accession # P09055-1 His-Pro GGGSGGGS Basic Tail N-terminus C-terminus
source short :
CHO
USD :
612 USD
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.