product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat TRANCE/RANK L/TNFSF11 Protein
catalog :
9366-TN-025
quantity :
25 ug
price :
432 USD
more info or order :
citations: 5
Reference
Ayyasamy R, Fan S, Czernik P, Lecka Czernik B, Chattopadhyay S, Chakravarti R. 14-3-3ζ suppresses RANKL signaling by destabilizing TRAF6. J Biol Chem. 2024;300:107487 pubmed publisher
Meng B, Yang B, Qu Y, Liu Y, Wu D, Fu C, et al. Dual Role of Interleukin-20 in Different Stages of Osteoclast Differentiation and Its Osteoimmune Regulation during Alveolar Bone Remodeling. Int J Mol Sci. 2023;24: pubmed publisher
Liu Y, Ai Y, Sun X, Meng B, Chen X, Wu D, et al. Interleukin-20 Acts as a Promotor of Osteoclastogenesis and Orthodontic Tooth Movement. Stem Cells Int. 2021;2021:5539962 pubmed publisher
Zeng Y, Zhou M, Chen L, Fang H, Liu S, Zhou C, et al. Alendronate loaded graphene oxide functionalized collagen sponge for the dual effects of osteogenesis and anti-osteoclastogenesis in osteoporotic rats. Bioact Mater. 2020;5:859-870 pubmed publisher
Tang Q, Hu Z, Jin H, Zheng G, Yu X, Wu G, et al. Microporous polysaccharide multilayer coated BCP composite scaffolds with immobilised calcitriol promote osteoporotic bone regeneration both in vitro and in vivo. Theranostics. 2019;9:1125-1143 pubmed publisher
product information
brand :
R&D Systems
master code :
9366-TN
SKU :
9366-TN-025
product name :
Recombinant Rat TRANCE/RANK L/TNFSF11 Protein
unit size :
25 ug
seo description :
The Recombinant Rat TRANCE/RANK L/TNFSF11 Protein from R&D Systems is derived from CHO. The Recombinant Rat TRANCE/RANK L/TNFSF11 Protein has been validated for the following applications: Bioactivity.
target :
TRANCE/TNFSF11/RANK L
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in NaH2PO4, NaCl and EDTA with BSA as a carrier protein.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>85%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Rat
observed molecular weight :
33-38 kDa, reducing conditions
theoretical molecular weight :
29 kDa
details of functionality :
Measured by its ability to induce osteoclast differentiation of RAW 264.7 mouse monocyte/macrophage cells. The ED50 for this effect is 2.5-15 ng/mL in the presence of 2.5 ╡g/mL of a cross-linking antibody, Mouse Anti-polyHistidine Monoclonal Antibody (Catalog # MAB050R ).
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Rat TRANCE/RANK L/TNFSF11 Protein Bioactivity
accessionNumbers :
XP_008769150
applications :
Bioactivity
source :
CHO-derived Recombinant Rat TRANCE/RANK L/TNFSF11 Protein
USD :
432 USD
alt names :
CD254, CD254 antigen, ODF, OPGL, OPGLOPTB2, Osteoclast differentiation factor, Osteoprotegerin ligand, RANK L, RANKL, RANKLreceptor activator of nuclear factor kappa B ligand, Receptor activator of nuclear factor kappa-B ligand, sOdf, TNF-related activation-induced cytokine, TNFSF11, TRANCEODFhRANKL2, tumor necrosis factor (ligand) superfamily, member 11, tumor necrosis factor ligand superfamily member 11
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.