Recombinant Rat TRANCE/RANK L/TNFSF11 Protein, CF | R&D Systems 9366-TN-025/CF product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat TRANCE/RANK L/TNFSF11 Protein, CF

catalog :

9366-TN-025/CF

quantity :

25 ug

price :

432 USD

citations: 4

Reference
Meng B, Yang B, Qu Y, Liu Y, Wu D, Fu C, et al. Dual Role of Interleukin-20 in Different Stages of Osteoclast Differentiation and Its Osteoimmune Regulation during Alveolar Bone Remodeling. Int J Mol Sci. 2023;24: pubmed publisher
Liu Y, Ai Y, Sun X, Meng B, Chen X, Wu D, et al. Interleukin-20 Acts as a Promotor of Osteoclastogenesis and Orthodontic Tooth Movement. Stem Cells Int. 2021;2021:5539962 pubmed publisher
Zeng Y, Zhou M, Chen L, Fang H, Liu S, Zhou C, et al. Alendronate loaded graphene oxide functionalized collagen sponge for the dual effects of osteogenesis and anti-osteoclastogenesis in osteoporotic rats. Bioact Mater. 2020;5:859-870 pubmed publisher
Tang Q, Hu Z, Jin H, Zheng G, Yu X, Wu G, et al. Microporous polysaccharide multilayer coated BCP composite scaffolds with immobilised calcitriol promote osteoporotic bone regeneration both in vitro and in vivo. Theranostics. 2019;9:1125-1143 pubmed publisher

product information

master code :

9366-TN/CF

SKU :

9366-TN-025/CF

product name :

Recombinant Rat TRANCE/RANK L/TNFSF11 Protein, CF

unit size :

25 ug

description :

The Recombinant Rat TRANCE/RANK L/TNFSF11 Protein, CF from R&D Systems is derived from CHO. The Recombinant Rat TRANCE/RANK L/TNFSF11 Protein, CF has been validated for the following applications: Bioactivity.

target :

TRANCE/TNFSF11/RANK L

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in NaH2PO4, NaCl and EDTA.

conjugate :

Unconjugated

purity :

>85%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Rat

observed molecular weight :

33-38 kDa, reducing conditions

theoretical molecular weight :

29 kDa

details of functionality :

Measured by its ability to induce osteoclast differentiation of RAW 264.7 mouse monocyte/macrophage cells. The ED50 for this effect is 2.5-15 ng/mL in the presence of 2.5 ╡g/mL of a cross-linking antibody, Mouse Anti-polyHistidine Monoclonal Antibody (Catalog # MAB050R ).

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Rat TRANCE/RANK L/TNFSF11 Protein Bioactivity

accessionNumbers :

XP_008769150

applications :

Bioactivity

source long :

Chinese Hamster Ovary cell line, CHO-derived rat TRANCE/TNFSF11/RANK L protein Arg72-Asp318, with an N-terminal 6-His tag

source short :

CHO

USD :

432 USD

alt names :

CD254, CD254 antigen, ODF, OPGL, OPGLOPTB2, Osteoclast differentiation factor, Osteoprotegerin ligand, RANK L, RANKL, RANKLreceptor activator of nuclear factor kappa B ligand, Receptor activator of nuclear factor kappa-B ligand, sOdf, TNF-related activation-induced cytokine, TNFSF11, TRANCEODFhRANKL2, tumor necrosis factor (ligand) superfamily, member 11, tumor necrosis factor ligand superfamily member 11

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.