product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human ADAM10 Protein, CF
catalog :
936-AD-020
quantity :
20 ug
price :
618 USD
more info or order :
citations: 24
Reference |
---|
Moss M, Bomar M, Liu Q, Sage H, Dempsey P, Lenhart P, et al. The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events. J Biol Chem. 2007;282:35712-21 pubmed
|
Hinkle C, Sunnarborg S, Loiselle D, Parker C, Stevenson M, Russell W, et al. Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency. J Biol Chem. 2004;279:24179-88 pubmed
|
product information
brand :
R&D Systems
master code :
936-AD
SKU :
936-AD-020
product name :
Recombinant Human ADAM10 Protein, CF
unit size :
20 ug
seo description :
The Recombinant Human ADAM10 Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human ADAM10 Protein, CF has been validated for the following applications: Enzyme Activity.
target :
ADAM10
category :
Proteins and Enzymes
buffer :
Supplied as a 0.2 ╡m filtered solution in MES, NaCl, ZnCl2,Glycerol and Brij-35.
conjugate :
Unconjugated
dilution :
Enzyme Activity
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
60 kDa, reducing conditions
theoretical molecular weight :
52 kDa
gene symbol :
ADAM10
details of functionality :
Measured by its ability to cleave a fluorogenic peptide substrate Mca-KPLGL-Dpa-AR-NH2 (Catalog # ES010 ). The specific activity is 20 pmol/min/╡g, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
O14672
applications :
Enzyme Activity
source :
Sf 21 (baculovirus)-derived Recombinant Human ADAM10 Protein, CF
USD :
618 USD
alt names :
a disintegrin and metalloprotease domain 10, a disintegrin and metalloproteinase domain 10, AD10, ADAM 10, ADAM metallopeptidase domain 10, CD156c, CD156c antigen, CDw156, disintegrin and metalloproteinase domain-containing protein 10, EC 3.4.24, HsT18717, kuz, Kuzbanian, Kuzbanian protein homolog, MADM, MADMEC 3.4.24.81, Mammalian disintegrin-metalloprotease
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.
more info or order :
company information

R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
browse more products
questions and comments