product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat IL-17A/F Heterodimer Protein
catalog :
9340-IL-025
quantity :
25 ug
price :
460 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Travis O, White D, Pierce W, Ge Y, Stubbs C, Spradley F, et al. Chronic infusion of interleukin-17 promotes hypertension, activation of cytolytic natural killer cells, and vascular dysfunction in pregnant rats. Physiol Rep. 2019;7:e14038 pubmed publisher
product information
master code :
9340-IL
SKU :
9340-IL-025
product name :
Recombinant Rat IL-17A/F Heterodimer Protein
unit size :
25 ug
description :
The Recombinant Rat IL-17A/F Heterodimer Protein from R&D Systems is derived from CHO. The Recombinant Rat IL-17A/F Heterodimer Protein has been validated for the following applications: Bioactivity.
target :
IL-17A/F Heterodimer
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Rat
observed molecular weight :
12-30 kDa, reducing conditions
theoretical molecular weight :
15 kDa (IL-17A) 15 kDa (IL-17F)
details of functionality :
Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. Yao, Z. et al . (1995) Immunity 3 :811. The ED50 for this effect is 3-18 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Rat IL-17A/F Heterodimer Protein Bioactivity
accessionNumbers :
Q61453 (IL-17A) Q5BJ95 (IL-17F)
applications :
Bioactivity
source long :
Chinese Hamster Ovary cell line, CHO-derived rat IL-17A/F Heterodimer protein Rat IL-17A (Ala18-Ser150 (Ile46Leu)) Accession # Q61453 Rat IL-17F (Arg29-Ala161) Accession # Q5BJ95 N-terminus C-terminus
source short :
CHO
USD :
460 USD
alt names :
CTLA8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, Cytotoxic T-Lymphocyte-Associated Protein 8, IL17, IL-17, IL-17A, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17A, interleukin-17A
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.